Simple modified amino acid stopped the onset of Parkinson's disease in the early stages

[PDTom]

nature.com/articles/s41467-...

[Gcf51]

A search of Acetyl-DL-leucine yields: AI; Acetyl-DL-leucine (ADLL) is a medication that's been used to treat acute vertigo and dizziness, and to improve central vestibular compensation. It's also been shown to help with cerebellar ataxia, which is a symptom of some lysosomal storage diseases (LSDs).

Also, yields L-leucine which I am sure is not the same thing.

I wonder if I can get my MDS to prescribe.

[Gcf51]

 Bolt_Upright The linked Article, may be of interest to you -- REM sleep disorder.

[Bolt_Upright in reply to Gcf51]

Thanks for thinking of me. I am keeping an eye on this.

[park_bear]

Only two patients without placebo control, but a very encouraging report! Patients showed improvement as of the fourth week of treatment. This substance is an over the counter medication in France referred to as Tanganil. In a different trial that used the same dosage, it was uptitrated as follows:

jamanetwork.com/journals/ja...

"a 2-week uptitration scheme (initial dosage of 1.5 g acetyl-DL-leucine per day taking 1 tablet of 500 mg each 3 times per day in the first week, 3 g per day taking 2 tablets of 500 mg each 3 times per day in the second week). Full dosage (5 g per day taking 3 tablets in the morning, 3 tablets at noon, and 4 tablets in the evening of 500 mg each) was maintained for 4 weeks. In the case of adverse events (AE), a down-titration to a minimum dosage of 1.5 g per day was permitted at the investigators’ discretion. Medication intake was at least 30 minutes before and 2 hours after a meal"

Additional detail:

"Acetyl-leucine (AL) has been found to have symptomatic and disease-modifying effects in animal models of lysosomal storage disorders (LSD)... Several formal LSD clinical trials with the active L-enantiomer, including our recent double-blind, placebo-controlled crossover phase 3 trial in NPC8 , found that N-acetyl-L-leucine had rapid beneficial effects on neurological signs and symptoms and an excellent safety profile. The agent enters enzyme-controlled pathways that correct metabolic dysfunction and improves energy adenosine tri-phosphate (ATP) production...."

Avoid alcohol: "re-appearance of dream enactment due to the use of alcohol"

"oral ADLL therapy partially reversed the decline of the DAT-SPECT binding ratio, almost normalizing it after about 2 years of treatment"

[Despe in reply to park_bear]

PB, shall I rush to Amazon??

[PDTom in reply to park_bear]

thanks for the tip about ‘tanganil’ from france.

I have ordered it.

but are you sure that it contains acetyl-DL-leucine?

Tanganil ® = Acetyl-Leucine

[park_bear in reply to PDTom]

vinmec.com/eng/article/what...

"The main active ingredient of tanganil is Acetyl-DL-leucine along with some excipients such as wheat starch, pregelatinized corn starch, calcium carbonate, magnesium stearate, the volume is just enough for 1 tablet. "

[PDTom in reply to park_bear]

Thank you very much!

then i'll start taking 10 tablets of 500mg = 5 grams after my stay in cuba.

if this were to show an effect after about 4 weeks, it would be a sensation for me. by effect, I mean a partial reversal of the symptoms. I have already stopped parkinson's almost 100% with the alternative healing methods By the way, I have been taking 5mg lithium for about 2 weeks, which has improved my already good mood even more!

everything seems to be going well, thank you very much for your help!

[PDTom in reply to park_bear]

i don't want to brag, but the doctors in cuba are also delighted with my state of health! to be in such good shape here almost four years after my diagnosis and without medication is very surprising. well, i'm investing a lot of time and money to fight parkinson's. but in the end it's the result that counts and i want to prove that i can do it without the classic medication!

[Lana666 in reply to park_bear]

When I googled for tangonyl it showed me "prescription only ". How did you get over the counter?

[Gcf51]

Another good Article: Acetylation turns leucine into a drug by membrane transporter switching. nature.com/articles/s41598-...

[PDTom]

I come from Germany and the doctors here are very careful and very conservative! The fact that this report was published tells me that the doctors are very sure. I have been following the news on the internet every day since my diagnosis in December 2020. I still don't take any medication and my condition is very, very good thanks to the alternative healing methods I use. I am currently undergoing treatment in Cuba (Havvan/Ciren/Neuroepo). The doctors are thrilled with me! But this news (Acetyl-DL-Leucine) is the best news I have read in years! I'm going to get "Acetyl-DL-Leucine" and take it after my stay in Cuba. tomparkinson.de

[Gioc]

thanks PDTom ,

Great news!!!

I think I will look into the topic further and if it does not have major contraindications I could take it.

⭐️ ⭐️⭐️⭐️⭐️

Congratulations for your successes and for your truly interesting protocol.

greetings from Italy

Como lake today

[Gcf51]

Same subject 4 days apart healthunlocked.com/cure-par...