Hello, Im trying to find some clear guidance on the CA125 test. I was diagnosed in March with HGSOC stage 4. My CA125 was about 5,000. I had 4 chemos and it came down to about 800. I then had a successful debulk. 6 weeks later (last Tuesday) my 5th chemo and CA125 was back up around 1,200. I know the onc staff are keen we don't take too much notice but it would be comforting to understand more. I'd be so grateful if someone can direct me to a good site/article that explains the relationship between CA125 and OC. I'd also love to hear other peoples experience and whether they were similar to me. Is it possible to survive with high CA125 long term or can I expect my CA125 to suddenly drop to a normal level? With only one treatment left Im wondering if I'll ever get down below 35.