Good CA125 result again

[drdu]

Hi everybody.

Just to report that my recent CA125 result was very good again, at 6, same as 6 months ago. I am very fortunate that ibuprofen appears to work as an anti-cancer agent for me. Please see my previous posts. I assume that my cancer must have the mutated PIK3CA gene, as per the research mentioned in my posts, and others, in January and February this year.

Best wishes to you all.

Love,

Eileen x

[Luci22]

Hi Eileen, that is great news! Looks like it is working well for you. How much ibuprofen do you take daily? How does the dosage convert to other NSAIDS such as baby Aspirin?

Would the mutated PIK3CA gene be discovered through genetic testing? I assume you need to ask the oncologist to be tested for it?

Thanks and wishing you continued health.

Luci

[drdu in reply to Luci22]

The mutated PIK3CA gene would be found in the tumour material removed at surgery. My oncologist tells me that these days the genome of the tumour is analysed routinely, and so it should be discovered if they look for it, I understand.

I take ibuprofen 400mg 3 times a day with food, along with omeprazole 20mg once a day to protect my stomach from the effects of ibuprofen. You would need to check with your doctor about taking that, as it is not without risks and doesn't suit everyone. Aspirin is in dose of 75mg once daily, ie one "baby aspirin" daily.

The trouble is that many oncologists in UK seem to be reluctant to get involved in pursuing this, in my experience. You may have better luck with asking them re using aspirin than ibuprofen.

Best wishes.

Eileen

[gmc920]

Wonderful news! So happy for you! 😊💕

Best wishes,

Gina

[drdu in reply to gmc920]

Sorry Gina. I don't seem to have replied to you. Thanks very much. All best wishes to you.

Eileen xx

[Katmal-UK]

Good news! Whatever you are doing, keep doing it! xx

[drdu in reply to Katmal-UK]

Thanks Katmal. See above reply to Gina. Almost 10years since diagnosis, and almost 5 years since last chemo.

Best wishes.

Eileen x

[Sushmita2304]

Hi Eileen,

That is so good to hear.. Very very happy for you dear ❤️😍

Regards,

Sushmita

[drdu in reply to Sushmita2304]

Thank you very much Sushmita.

All best wishes.

E xx

[Maus123]

Keep going, Eileen. That's fortunate indeed and it's great it pays off for you. I'm still on low dose ASS at the moment but it's a guess rather than an informed choice, as I haven't done genetic testing yet. xx. Maus

[drdu in reply to Maus123]

It is worth a try.

Best wishes.

E xx

[Levanah in reply to Maus123]

Me neither Maus. Genetic testing is now something they do for newly diagnosed Ovarian cancer I believe but those already diagnosed or with recurrence it isn’t routinely done. Scotland is also ahead of England with genetic testing or genomic tissue testing .

Xx

[drdu in reply to Levanah]

Yes, I have not been tested. I asked at last appointment to be tested, on the original cancer tissue, but they said it could be done, but neither my oncologist or I would get the results, which seems a bit pointless for the patient! Or the oncologist! I can only take it that it is some trial they are doing. I am in Glasgow. I asked for it to be done anyway.

E xx

[thomas62]

So great to hear such good news from one of our lovely ladies. Keep it up. Gwen xx

[drdu in reply to thomas62]

Thank you very much Gwen!

Best wishes.

Eileen xx

[IrishMollyO]

Hi Eileen

I have been following your progress for a good few years now and I'm happy to read you are still winning. I'm still taking 75m aspirin which were prescribed many years ago to prevent a stroke. It may explain my 5 year NED . I have since had two recurrences in my lymph nodes. My stage 3 c high grade serous PPC was inoperable so no tissue to test for

PIK3CA. However unrelated breast cancer in 2017 which required a mastectomy gave me the opportunity to be tested for the mutated BRCA genes. Results was negative but I wonder if Genetic scientists hold on to all tissue that they test. Perhaps not and that may well be a silly question!

Meanwhile I'm delighted with your positive news Eileen.x

X. 💚💕

[drdu in reply to IrishMollyO]

I think they do hold on to tissue Molly. Good luck! Best wishes.

E xx

[IrishMollyO in reply to drdu]

Thank you Eileen

X. 💚💕

[drdu in reply to IrishMollyO]

xx

[Lind58]

Amazing news ❤️ What a blessing!

[drdu in reply to Lind58]

Yes it is amazing. I am very lucky.

All best wishes.

E xx

[Spirit22]

Fantastic News! Very Best wishes Lesley Xx

[drdu in reply to Spirit22]

Thanks very much Lesley.

All best wishes.

Eileen x

[Levanah]

So pleased all is going well Eileen. Thank you so much for posting about NSAID’s. Jane McLelland and the COC trial in London use these re-purposed drugs to treat cancer. It’s very interesting isn’t it?

I’m going to start taking Aspirin 75mg to see if it helps me.

I see you’re a retired GP. I’m a medically retired Palliative Care CNS. It’s very difficult being on the other side with the knowledge we have isn’t it?

Much love to you

Diane xxx 💜

[drdu in reply to Levanah]

Yes, it is difficult. Have read your story. Good luck with Aspirin. Thank you very much.

Love,

Eileen x

[Lizjj]

Hi Eileen. Really good news! My question is , do you have any idea as to whether Ibuprofen gel rubbed onto the tumor area could be affective? Just wondering if this could be a possibility if tumor was located on one spot and thus avoiding stomach problems? XXXXXX

[drdu in reply to Lizjj]

I am sorry I don't think that would work as the ibuprofen attacks cancer cells circulating in the blood, to my understanding, in some way stopping them settling in one spot as a secondary growth or metastasis.

Sorry. Thanks for your support.

Best wishes.

Eileen x

[LittleSan]

So delighted to hear your news. Long may it continue. 💐😘

[drdu in reply to LittleSan]

Thank you very much. Good luck with the trial you are on.

All best wishes.

Eileen x

[Mptelesca]

Wonderful news! Ca of 6 is a dream! Mine loves to stay in the teens! Very interesting about ibuprofen. I always used as its the only thing that works on spin for me. I thought it would go against my chemo and parp.

Thank you for sharing your encouraging news and information. I’m going back on Advil!

Xox

Marisa

[drdu in reply to Mptelesca]

As long as you are not on strong chemotherapy, ibuprofen (Advil) should be ok, but be sure to check with your oncologist first, as you might not be suitable to take it (it can cause kidney damage and stomach irritation/bleeding), and always take omeprazole 20mg along with it, or something similar to protect your stomach. Do check with your doctor.

All best wishes.

Eileen x

[Melody6]

That’s great news, Eileen - very, very pleased for you 🍾 . With love, Mel xx

[drdu in reply to Melody6]

Thank you very much Mel.

Love,

Eileen xx

[belle1958]

So happy for you x

[drdu in reply to belle1958]

Thanks very much Belle. Best wishes.

Eileen xx