Abraxane -chemo used in Ireland for O.C.?

[GNM1]

Hi everyone,

following on from some other posts where people had a severe allergic reaction etc. to Taxol, a friend sent me a link - Abraxane also called nab-paclitaxel, according to British Gynaecological Cancer Society (BGCS) Epithelial Ovarian / Fallopian Tube / Primary Peritoneal Cancer Guidelines, is given in the UK to patients who are allergic to or do not tolerate paclitaxel. I know it's used for other types of cancer here in Ireland but has anyone heard of it been used for Ovarian Cancer? It seems it is a type of taxol drug but carried into the body via albumen, where as the paclitaxel & docetaxel are dissolved in solvent.

[Hidden]

Hi

I haven't heard of this drug for OC - I'm also in Ireland - if you get any further information will you let us know?

Best wishes

Juliet

[GNM1 in reply to Hidden]

Absolutely! It's used to treat pancreatic cancer, not sure about protocols/licencing for O. C. Some say it's the solvent the drugs are resolved in that patients are allergic to, but Abraxane is carried in a protein -albumen which is more easily accepted by human body, it's also more expensive.

All the best G.

[Hidden in reply to GNM1]

Thanks!

[Perthgirl]

Hello there! My first 6 chemo sessions were of Abraxane with carbo, all given by IV although I had a IP port. I then went on to have 18 IV/IP with Cisplatin and Paclitaxel. Sorry I can't be of more help but do know my oncologist was insistent that I have the Abraxane first. The only major side effect I had with it was low Neutrophils. Good luck xx

[GNM1 in reply to Perthgirl]

Thanks so much for your reply, may I ask if you're treatment was IN Ireland? (or is your name a clue ? 😊) Also was it for Ovarian Cancer? I only ask because I'm unsure of licensing /protocol issues -seem to vary a lot. One other Q, had you had an allergic reaction to Taxol? Again, I ask because I've heard Dr's are reluctant to re-challenge a patient who had an anaphylactic reaction to any of the Taxol drugs. They don't seem to give IP ports either. Great to hear you had Abraxane & Carbo -you're the first person I've come across -thank you for sharing

Mind you -followed by another 18 sessions -sounds rough -hope it went well for you and that you're happily out the other side now😘 Really appreciate your input and anything else you might observe etc. Thank you. G. xox 😘

[Perthgirl]

Hi again G, yes, this was for OC stage 3B in Australia - Abraxane was used as an interim treatment for me until they could begin the ip as my onc wanted to begin asap (2 weeks after debulking op!) But said if i battled with ip he would revert to abraxane. I am out the other side now, 4 months post chemo with 1 st PET scan due mid Oct, so fingers crossed. Other than neutrophils constantly low and very little appetite i didn't have too many issues with abraxane. The metallic taste in your mouth is strong but i drank water with lemon or ginger constantly to counteract. Hope this helps and please let me know how you get on. Kind regards Stacey x

[GNM1 in reply to Perthgirl]

Thanks Stacey,

Go you 🤗🙏 -keep the good work up 🤗 I'll X my fingers for you too 😜.

That sounds good -now if only my oncologist will give Abraxane to me .

Thanks again -be well ❤️ G x

[Perthgirl in reply to GNM1]

Stay strong, and will follow your progress. Take good care of yourself xx

[rossnbren in reply to Perthgirl]

Hi Perth girl.. Do you go to the Ivy Suite... I live in Albany but spent 7 months in Perth AUS having my treatment there last year and early this year..,coming up for my 9 months after chemo check this week ... so far so good. I also am stage 3B OC. ... all the very best to you...

[Perthgirl]

Hello again! I was operated on at sjog Subi and Chemo at Genisis cancer care in joondalup, pity as we would have met otherwise. So good to hear you are doing well and hope your next check goes really well. How lucky are you to live in Albany G, absolutely love that area and we come down as often as we can, generally in winter 😀. Please let me know how your check up goes. Take good care of yourself in the meantime x x