Tried to post this yesterday but not sure it went through. I've been with my sister this week for the beginning of her trial. She received Keytruda this first day and then CR 207-a Listeria based infusion-the second day. She experienced a dull headache day one. Her reaction after the Listeria infusion was a bit worse. She had pretty significant rigors for almost an hour after infusion and then had a fever for about 12 hours. The next few days she was achey and very tired. She is so incredibly strong and I continue to be in awe of her determination to battle valiantly.