Clinical Trial

[kristinaapril]

Hey everyone, I hope you are doing well. For the last two weeks, my mom and I have been anxiously waiting the results from her CA125 and her CT scan. Today, we heard back on the CA125, which was 8; the lowest it's every been (was 9 after front-line; and 10 one month after). We also got paperwork mailed from the clinical trial she is participating in (more on that in a bit); so we think her CT came back well, as you need to be NED to participate. We have an appointment with the gynea-oncologist Tuesday, so we should hear more about that then.

For all the Americans out there, I wanted to bring your attention to a clinical trial that you might be available for you if you are ned. My mom's friends reoccurrence got detected from the trials routine CT scans; though her CA125 was normal. Because of this, mom is adamant about 3 month scans; and with her deductible being $250, it adds up quick. Bit sad isn't it; going on the clinical trial so the tests and scans are free.

The trials is on diet and physical activity vs usual activity and improving progression free survival. Rather intrusive trial with most of the consultations being on telephone calls with the counselor.

Here is the link if anyone is interested in looking in it: clinicaltrials.gov/ct2/show...

Kris x

[January-2016-UK]

Hello Kris, I had a look at this trial even though it’s only available in the States. Most thought provoking. As it’s phase 3, good expectations have presumably been gained from previous phases. Can’t see as if there’s anything to lose from participating even without considering the scans, etc.

All the best!

[kristinaapril in reply to January-2016-UK]

Good motivation for mom and I to go on a diet as well 😜. We may have indulged a bit too much this weekend!

[January-2016-UK in reply to kristinaapril]

Of course, it's your Thanksgiving celebrations this weekend. Hope you enjoyed yourselves with lots of good food and company. I usually lose half-a-stone before Xmas so I can over-indulge to my heart's content without worrying about the consequences but methinks this would not be a good idea this year having regard that my taxol dose is loosely based on weight and might get reduced.

[Bluehen]

I could not get the link to work. What is the name of the trial?

Thank you

[kristinaapril in reply to Bluehen]

It is GOG-205

[Lily-Anne]

Fingers crossed for a good result from the trial

LA

[Bluehen]

Can you share more about the diet and exercise on this trial ?

[kristinaapril in reply to Bluehen]

I just copied this from the trial website, but I can give you more information on Tuesday, when my mom goes to the trial appointment.

"Participants receive a dietary intervention designed to promote increased levels of plasma carotenoids, control weight, and to ensure adequacy of micronutrient intake. Participants also undergo a physical activity intervention comprising a moderately low aerobic regimen to raise the usual activity level. Participants also undergo face-to-face counseling, receive educational materials and counseling focused on how to read food labels to estimate grams of fat per serving and serving size, and undergo telephone counseling by a lifestyle intervention counselor twice a week for 4 weeks, then weekly for 2 weeks, twice a month for 5 months, monthly for the subsequent 6 months, and then once every other month for 12 months. Participants complete daily fat gram and step diaries at least three times per week."

[chrissapam]

...sounds very interesting...wish they would separate the counselling from the nutrition advice for some participants though...maybe will at the next phase! xx