I'm on weekly taxol at the moment and have to have an intravenous dose of piriton before it starts half an hour before along with a steroid. Taxol can cause an allergic reaction which is why it has to be done apparently. Now I'm feeling well , I'm 44 but the piriton knocks me for 6 and I feel like I've been drugged, I can't keep my eyes open although it's hard to properly sleep as I'm doing the cold cap. It's not a nice feeling and I'm like it now in the car on the way home! Does this affect anyone else out there like this?