adalimumab

[Jfw24]

I’m starting adalimumab after being on methotrexate for three years, how easy is it on your system? I’ve had no issues with methotrexate but couldn’t cope with sulfasalazine or leflunomide.

[dwsurquhart]

I had a myriad of side effects from Adalimumab.

Mtx was horrible for me, leflunemide and plaquinel were not good either.

Sulfasalazine was alright, did not work for me, but no side effects.

Prednisone screwed with my head.

Got onto Kineret (IL1 inhibitor) daily subQ injection, did not work.

Been on Tocilizumab for 8 years? Now and it is still working.

Hopefully they do not Adalimumab works for you. If you have any side effects CALL YOUR RHEUMATOLOGIST! That is the only advice I can give.

BE YOUR OWN BEST ADVOCATE!!!!!!

[Brushwork]

The thing is that we are all so different in the way we react to medication. Although I suspect if research were carried out we would find that people who can’t tolerate x generally can’t tolerate y…. Sadly we are not there yet.

It might be the one medication that gives you relief. It’s also a biologic and generally they are easier on our systems, but not always.

Godo luck and go gently

[Tealblue2]

I’ve been on it since July. I’ve had no side effects from it and it has worked better than methotrexate for me. They are increasing my does of it this week as the effects don’t last / weeks. But after about a month on it I was able to walk again and got benefits with no side effects

[netballnow]

I have been on Adalimumab, fortnightly, since April 23. Previously in hospital for 3 days unable to move and zonked out on painkillers. Over 20 months they tried me with Sulfasalazine, Prednisolone (when desperate) and all manner of painkillers.

10 days after starting on Adalimumab I was pain free and have never looked back. I still take 25mg of mtx weekly but they are hoping to reduce that in January and even to lengthen the injection time. Reaction to Adilamumab is a constant chesty cough which I will put up with as opposed to pain. I wish you well.

[flowerlover]

Adalimumab in the form of Imraldi was a complete game changer for me. I was on it from 2020 till early 24. I had a mild sore throat in the early days & a headache the day after the injection but this settled down. The excruciating wrist & hand pain, all other joint pain etc took several weeks to settle completely but my consultant advised continuing prednisolone to tide me over this period. I was back to my normal self & remained healthy & infection free despite having two very small germ spreading grandchildren!

As a cost cutting measure (I think) I was changed to Hyrimoz. This is still adalimumab and supposedly 'the same'. The RA is still wonderfully controlled but I have had infection after infection almost since the month I changed.

Luckily I have an understanding consultant & he had it changed back to Imraldi last month. I expected to have to argue my case but no. 🤞

I am keeping everything crossed that adalimumab works for you as it worked for me. Good luck

[Bookworm55]

I was on it between July 23 and Jan 24 but my rheumatologist felt it didn’t work well enough for me. My only side effect was a rash - raised bumps on my legs which itched a bit. My rheumatologist was sceptical that this was a side effect of Adalimumab but since then I’ve read on here that it is ! Since June this year I’ve been on Rituximab infusions which have so far been very successful in controlling my pain and swelling.

[York54]

Hi, I have been on it since February , injection once a fortnight. It has been great ,within a week , my joints in my hands especially were pain free and less swollen. I hope it works as well for you, good luck .

[Chester1975]

Hi

The only side effects I have had fr this injection is redness at the injection site which I keep clean with an antiseptic body wash, terrible headache for two days after the injection and slight pain in my right side, possible liver, so I make sure I drink plenty of water.

Hopefully you’ll be fine but keep a note of any side effects and if you are concerned, speak with your Rheumatologist or nurse.

😁

[anne999]

I was on Idacio which is a biosimilar, felt great on it, but despite having my bloods taken every month my prescriber never checked them, it was only at a routine appt that my ALT was noticed to be 364 and had been going up for 6 months

[PCStrawberry]

Wife had zero side effects from Humira (adalimumab). MTX wasn't permitted, due to kidney disease. HCQ wasn't very effective, even paired with prednisone. Of course, as usual with biologicals, her body found a neat trick to go around Humira and it simply quit working after about 9 months. Currently, she's on Enbrel (etanercept) and it's modestly effective, but only paired with prednisone and it's simply not going to work long term. We've been waiting since early last month to get back into the rheumatologist to find a better solution. Currently, we're booked for 1/15, hopefully it will be sooner. And, yes, we do wait, and struggle, in the USA, even with egregiously high costs. Best wishes in achieving your goals.

[Alozz]

I'm on MTX and Sulfasalazine and recently went on to Adumilab subcutaneous every 2 weeks. First 2 times, a bit tired but now I.m fine... no neg effect but very good effect on symptoms. Mtx was worse. Still get tired but that could be illness or drugs or age....

[purplecyclist in reply to Alozz]

was that as well as MTX and Sulfasalazine or instead of it? this could be my next step so I am curious

[Jfw24 in reply to purplecyclist]

I’m on methotrexate and adalimumab, sulfasalazine didn’t agree with me so they stopped that over a year ago