Hello, my husband had an appointment with the Rheumatology nurse today. He is on tocilizumab but has had to have half dose as his liver blood results are too high. It is not as effective and he is developing problems with his hands. He is seeing the physiotherapist and an steroid injection was discussed, but the nurse seemed unsure about it. Fortunately the Consultant was free and she spoke to him. He said about changing my husband over to adalimumab, which my husband was happy to do - not least as he won't have to to the hospital for infusions every four weeks. Apparently it targets a different part of the inflammatory process. He has had four bouts of cellulitis since being on tocilizumab which had hadn't had before. He then had a phone call while out picking up medication in the pharmacy to say the doctor had looked at his notes and won't be putting him on adalimumab as his antibodies were high. He didn't even know that these had been checked! He is to continue with a half dose of tocilizumab while they review his notes.
The nurse said he was complicated. He has been trying to say this to them for several months but no-one has been listening. He has diabetes, is on clopidegrol (to prevent blood clotting, has a heart stent, diabetes type 2 and chronic lymphatic leukaemia (watch and wait, meaning he is not on any treatment for it). He also has pulmonary fibrosis and emphysema. Needless to say he feels very down about it tonight. Has anyone had similar problems with tocilizumab and were they able to find another medication that worked?
Many thanks.
El