alternatives to methotrexate

[Cal48]

just had 2 chest infections so have been off metho.

Can’t believe how well I felt without taking it but of course the aches came back even though I am on low dose lefluamide as well.Have been on it low dose both for years

Don’t like what metho does to me feel mixed up,knackered and get cross easily when I’m on it.

Any other drugs that work as well but not so debilitating ?

[bpeal1]

We are all so different that what works for one with no side effects does not work for another and/or has bad side effects. Contact your rheumatology team and tell them how much better you are feeling without the methotrexate and ask to try something else instead. In the meantime look at this page on the NRAS website that explains what all the different options are. nras.org.uk/information-sup...

[medway-lady]

I take Azathyoprine as have CKD and it works well. I think it's not prescribed so often now and I don't know if it would help you but worth asking about. Before this though I took the LEF on its own. The AZA has no side effects for me but obviously it might be different for you. I hope that helps.

[Cal48 in reply to medway-lady]

Thank you

[Madmusiclover]

Lots! Look at the medication leaflet on NRAS website.

[Maxie-47]

I took Methetrexate for many years. I used to dread my weekly injection because I felt so lousy (as you describe) for 24 hours after. I started to get chest infections so after much discussion with the rheumatologist I went onto hydroxychloroquine, which worked well to begin with - first year, then after a number of flare ups Barticinib was added. I was reluctant at first - because of the potential side effects and time will tell on that front. However, this combination has worked well for me and my RA is under control and I feel better in myself (at the moment) than I did on MTX. That said we are all different and respond differently. Hopefully looking at the options available and discussing with your rheumatologist will get you on what’s right for you.

[Cal48 in reply to Maxie-47]

Took hydrox. For many years but not recently since leflomidehas been added ,thank you

[Green230461]

They put me on humira and that worked well for eleven years good luck🍀

[Cal48 in reply to Green230461]

thank you