Methotrexate & over heating

[Old_Sceptic]

Hi all,

I've been taking Methotrexate after dinner on a Wednesday evening for three weeks now and I've been finding that I get super warm doing anything from around Friday lunchtime to Monday/Tuesday. I take the Folic Acid on Thursday evening. I also take a bunch of other drugs including anticonvulsants, anticoagulants and steroids.

I'm just wondering if anyone else has experienced feeling so hot, I literally feel like I'm burning up to myself and anyone else. The sweat is kind of embarrassing but there's nothing I can do 😕

Hope someone can give me some guidance or at least a towel 😁

[AgedCrone]

Ask if you can increase the FA. I do wonder why Rheumatologists still only prescribe FA once a week …..because it seems everybody they do that to …end up taking six a week!

If only you were a woman…you could try HRT!

I do hope your rheumy nurse can give you some more sensible advice!

[Old_Sceptic in reply to AgedCrone]

Many thanks for the information .

I don't think I could face HRT at the moment, I take enough drugs as it is. I will get onto the rheumy team and see what they suggest.

Many thanks

[Happy5]

I found just having RD made me feel like I have a temperature, I do get what you describe and put it down to the " battle" going on between the MTX and the white blood cells. The night I do my MTX injection as well as my anti- sickness I take 1 Co-codamol which helps reduce my symptoms including the increase of temperature.

If you have an advice line or similar contact your rheumy team and discuss they usually (especially the nurses ) have options to help.

[GordonEdin]

Well, methotrexate can affect people differently. Some a lot, some (like me) not badly at all. I have been on it for fifteen years.

However, my first thought is that active Rheumatoid Arthritis itself can cause significant fever symptoms. If you are taking steroids then I would guess that you do have significant RA symptoms.

For a period after developing RA, I was going to bed then having to get up half way through the night to towel myself off and change my pyjamas.

Your symptoms are also appearing a couple of days after your methotrexate dose rather than immediately after. If I am experiencing side effects I tend to notice them later the same day - I take my pills at breakfast time - and that tends to be a bit of queeziness and tiredness.

So, my suspicion would be that this is not necessarily an effect of the pills and may settle as the RA comes under better control. It took about four months to start to work for me and then two years for maximum effect.

However, seek advice if you still think that it is the pills!

[Old_Sceptic in reply to GordonEdin]

Thanks for your input. I do have significant RA but I also have a bad case of Sarcoids with granulomas etc everywhere. I have reached out to my Rheumy team and am awaiting their advice.

Many thanks

[Angels54]

Hi ,?I had this when I was on MTX 👍