Reaction to injections

[MaxineButler]

Hi I take methotrexate via injection and have just changed from Humira to Imraldi and now I am experiencing some odd reactions, I have blisters on my face wrist and large ones on my stomach which are both sore and itchy and weeping, I also have a very sore eye and nose. Has anyone suffered with this and can you give me any advice please

[Hidden]

Sorry I don’t take this medication but if you are having this sort of reaction please contact your team. Any rash can turn into a severe allergic reaction. Better safe than sorry.

[MaxineButler in reply to Hidden]

Thank you I have contacted my GP this morning and sent some pictures and I am just waiting for him to get back to me.

[oldtimer]

That sounds like a reaction all right! It's right to seek medical advice asap.

[medway-lady]

How are you now ?

[anglia]

Hi Maxine have had spots also sores in mouth and every few months bad flue symptoms but now no flu symptoms or mouth sores I use corsodyl toothpaste get a few spots on head otherwise nearly normal it took me a while to get used to methotrexate but without it I’d probably be in a wheel chair good luck and persevere but see you rummy doctor to be sure. x

[193639]

Hi Maxine,

I’ve been taking mtx Injections for over 7 years now, however I have not experienced any side effects you are suffering from. There have been thinning of the skin, issues with brittle nails and hair thinning. This was mostly in my first year and haven’t had any major side effects since. I’m sure you will get yourself checked out. I would suggest reading up on dietary needs, you may have to tweak a few items of food, lay off alcohol and stay out of direct sunlight until your body adjusts to the medication. There may be some effects with citric acid in some fruits such as grape fruit and tomatoes. Your diet may be too acidic therefore look to balance with some alkaline foods to restore the balance. For example, I take lemon juice with warm water which is acidic, however when taken with honey I believe when it is absorbed into the body it becomes alkaline.

Everybody is different and I am sure once the meds are in your system you’ll be fine. Look up what to eat and what not to as I believe your diet holds the key to feeling better.

This is just my opinion going on experience.

Take care a persevere, good luck to you Maxine

[Windonmyface]

I’ve been on Plaquenil since January and Methotrexate since April. My rheumy upped my dose of the latter to 20 mg (4 pills in morning and 4 pills at night) recently and now I have an itchy rash on my side. I don’t know if it’s related to the higher dose of MTX. I’m a little worried that it’s shingles even though I’ve had both doses of the better shingles shot. My thought is that both my RA and the MTX could be lowering my immunity to the point where I’ve gotten shingles despite being vaccinated for it. I’m wondering if others have had this problem, either with shingles or just a rash on the torso that is perhaps caused by MTX. I’m contacting my rheumy and my dermatologist tomorrow morning.

[Nyreedw]

I refused to change from Humira to Imraldi,under NICE guidelines you can't be forced to change and many who changed from original to biosimilars it is a bad decision. It doesn't work as well for them but going straight onto a biosimilar does. Biosimilars are not generic they are molecularly different. It has to be a joint decision between patient and consultant not forced on you x

[Knit12]

I had a bad skin reaction with many of the R.A. injections, it kind of reminds me of acne but some come up as blisters. So far I have had this with methotrexate, Humira and Benepali. My rheumatologist did some investigating with pharmacy and it appears they all have hydrochloric acid. I’m now on Tocilizumab but only had 2 and have taken an eye infection so now can’t take anything until it clears. I think you should take photos and send to your biologic nurse and consultant