Swollen Tongue: I have been on mtx and plaquenil for... - NRAS

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Swollen Tongue

shareasmile profile image
10 Replies

I have been on mtx and plaquenil for several weeks. Frequently my tongue feels swollen and feels like I burned it. Also have a metal taste. Has anyone else had this reaction? And does it get better?

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shareasmile profile image
shareasmile
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10 Replies
doctorpatg profile image
doctorpatg

I think you should speak with your doc rather than wait to see if it goes away. These drugs affect individuals so differently.

Barrister profile image
Barrister

Sounds a little like Burning Mouth Syndrome to me. Mine was caused by stress, but I believe that it can be drug induced. But definitely see your doctor. Clemmie

allanah profile image
allanah

I am waiting to see the oral consultant as they think I may have burning mouth syndrome caused by drug reaction. I get very very dry mouth which has swollen tongue and I get small lesions and raw spots on it.

Do pop to your dentist for advice and they can signpost you from there. Hope u feel better soon x

Hello BOB here

MTX has these contr-indications so would phone the clinic or GP ASAP

BOB

Trulyfedup profile image
Trulyfedup

I've had all those...the metaliic taste should be sorted..I would see your GP. MARYX

RichardG profile image
RichardG

I got similar symptoms when I increased the dose of mtx from 20 to 25 mg. sore tongue with swollen white areas. Very painful to eat. Went away after about 6 weeks when decreased dose to 15 mg and came back when tried to increase to 25 again. Now on humeria and 15 mg mtx and RA much better controlled.

southwest profile image
southwest

I have been on Methotrexate and Plaquinel and had a slightly sore tongue and gums feeling painful. However, it's really been my lips that have been very painful and blistered, so that is a different situation.. I have been taken off Methotrexate as a precaution. 3 months down the line the burning persists although the peeling skin is much better after I was given a steroid cream for a short time. I am still on Plaquinel- or the generic. I have read on various internet sites that a few people on Plaquinel have mouth issues. My Rheumatologist and GP do not seem to think it is an issue- I am only on 200mg daily but I sometimes wonder. You really have my sympathy as a burning mouth is very unpleasant. I hope you get some help with this soon. Best wishes.

shareasmile profile image
shareasmile

Many thanks everyone! I see my rheumy doc today and hopefully will get it resolved.

Rhodes62 profile image
Rhodes62

Hi yes I get this but I now usually associate this happens before a flare as it's not constant

Hi! I have had that metallic taste for a short time. My tongue never got swollen but mt tongue burns on and off. I use children's toothpaste when brushing my teeth. Anything else burns to much.

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