RISING EGR

[pigeonman]

I HAVE RECENTLY BEEN RELEASED FROM A 14 DAY HOSPITAL IN PATIENT STAY. THE STAY WAS A RESULT OF RSV VIRUS. SOME AMAZING THINGS HAPPENED WITH SOME OF MY BLOOD WORK. GOING IN MY EGFR WAS AT A 36 LEVEL. HOWEVER DURING THE STAY IT IMPROVED TO 50. HOW IS THIS POSSIBLE? THEY TOOK MY .05 FARXIGA AWAY FROM ME? THEY ALSO ADDED STEROROIDS AN REDUCED MY ELAVIL FROM 150MG TO 100 MG. EVERYTHING ELSE WAS THE SAME. MY ASSUMPTION IS THE STEROIRDS ALONG WITH INSULIN WOULD BE THE REASON FOR THE IMPROVEMENT. WHAT DO YOU THINK?

[jodaer]

Sorry to hear about your hospital stay but glad you are out and doing good. I don't have a clue about the increase in your eGFR but sounds like the change in meds might be the reason why. Are you staying on that protocol or are you back to the previous meds. It will be interesting to see where your eGFR is at your next labs. Be sure to let us know.

[Bassetmommer NKF Ambassador]

Interesting and concerning. Why would they take Farxiga away? NOT good and yes, the steroids could have produced that change, but steroids and CKD are not a good combination. It's like a cheap date, all goes well in the beginning but long term, not so much. Hospital doctors look for short term fixes and results. Their numbers are based on only your stay and not long-term outcomes. Also, if you are diabetic, having hospital food only and any added fluids such as an IV might show SHORT TERM improvement. Get to your regular doctors and have them check the medications.

[renegade70 in reply to Bassetmommer]

your absolutely right. a year in a half ago i was in the hospital for for 2 days all of my electrolytes were either high or low. of particular concern was very low potassium .so i was on intravenous potassium, magnesium etc for most of the time i was there. when i left and for about a month after my egfr was above 60 but then went back to 40 where it was and since that time has gone to 27 and as of last week was 44. so that 60 + turned out to be short lived. that was my experience. really hope it turns out better for pigeonman.

[Jimbo63]

Iv solutions possibly,cleaner diet

[barbara55109 in reply to Jimbo63]

My eGFR always goes up when I'm on IV fluids. Then again, the cause of my CKD is long time dehydration.

[Beachgirl32]

sorry you had a long stay in hospital. Super good your eGFR has improved that much. I know whenever I was in hospital my always seem to improve all the Iv fluid I think I never drank enough like I should have. Just keep updated labs up and you may want to watch if they stay the same now or go down or up.

[userotc]

Yes I'd agree with most that fundamentally hydration may be the reason. Even removing the farxiga may indirectly have contributed healthline.com/health/drugs... maybe the reduction of elavil.

[Hidden]

It's odd that they would remove the Farxiga, I hope you are back on it now. Amitriptyline is excreted by the liver, so it wasn't likely that. I would guess it was the IV fluids. Moving forward, perhaps increase your hydration on a daily basis. Congrats for surviving a hospital stay and coming home with good news!

[Helloyall]

The virus, dehydration and the resulting higher BG might have affected the kidney function going in. Correlate this to your BUN to see if this was indeed a function of dehydration. My former nephologist (don't need one anymore) said the best indicator of kidney function isthe creatine. You did not say what your EGFR was prior to getting sick. Watch your BG carefully- the steroids usedcto treat the virus will raise it.

[Blackknight1989]

Unless previously diagnosed with CKD before the virus, here are my thoughts. You did not have CKD, instead the virus caused AKI which will improve once the underlying cause is removed or also improves. FARXIGA or dapagliflozin will help significantly slow down CKD progression but isn’t known to significantly increase eGFR.

If you did have CKD prior to the virus and hospitalization the same principle applies. For example, after all my joint replacements my eGFR dropped to 10-12 and creatinine increased to 6/7. Slowly over a month or so those specific labs returned to my normal of eGFR 20 plus and creatinine about 2.9-3.4. So an assault to the body (virus causing hospitalization or major surgery) can cause a significant change in lab values for the worse for a short period of time with “recovery” to “normal” (your normal lab values not the range listed on the lab test results) after the critical phase is over and your overall health improves. Finally, I would do all I could to get the Farxiga prescribed again. Most all studies show the benefit to CKD patients both T2D and non-T2D. Link:

kireports.org/article/S2468...

As always my best to you with your journey back to good health!