Soluble vs enteric coated aspirin: Since Feb 202... - MPN Voice

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Soluble vs enteric coated aspirin

BrightNorka profile image
9 Replies

Since Feb 2024 I have been taking low dose soluble, effervescent aspirin (Upsarin -C) instead of enteric coated type.As per my hematologist there is no difference in the impact to the GI, however I still believe the soluble one would be reducing the bleeding risk. To avoid the bubbles, I drink the aspirin at least an hour after I drop it in the glass of water.

I have no GI issues with both aspirin types, so I cannot compare them in anything else.

Any sharing of your opinion, experience or known doctor advice re soluble vs enteric coated aspirin will be appreciated.

Stay positive and healthy 😊

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BrightNorka
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9 Replies
hunter5582 profile image
hunter5582

I have used both the enteric and chewable low dose aspirins as well as the new Vazalore forumation. I have not found any difference. I would think that some people are more sensitive to aspirin and may relative differently to the different formations.

summerdown profile image
summerdown in reply tohunter5582

I had issues taking aspirin and cardiologist changed me to clopidogrel. I take 1 low dose a day. no problems. I was taking enteric coated low dose aspirin.

Exeter21 profile image
Exeter21

I had to have the gastric coated aspirin always as have long term gastric problems. Ordinary or soluble types give me pain & soreness . The gastric ones work perfectly but from personal experience I cannot take others. Hence if you do not suffer previously from gastric problems then it doesn’t effect you 👌

AndyT profile image
AndyT

I’ve been on daily 75mg aspirin for 21 years and have digestive issues since the removal of my gallbladder 20 years ago, so I take the enteric coated aspirin as a precaution.

My haematologist tells me it works just as well as the non coated aspirin, so it doesn’t seem worth taking the risk of GI problems.

Hopetohelp profile image
Hopetohelp

I take enteric coated aspirin and don’t have an issue, touch wood

Carol0925 profile image
Carol0925

I take EC Aspirin with no side effects.

mhos61 profile image
mhos61

Hi,

I have taken the dispersible aspirin for nine years, I think I am in the minority. My GP at the time mentioned the bioavailability of dispersible aspirin was better than enteric coated, and I had read similar. I based my decision on that with the knowledge if it didn’t agree I would change to enteric coated.

I really must stress here that I have no gastric issues. I count myself really lucky when I read about the many people affected by gastric issues related to medication on the forum. I don’t take any proton pump inhibitors either. I do however take dispersible aspirin on a full stomach.

Leveret20 profile image
Leveret20

When I was first prescribed aspirin, it was the soluble form. I seem to remember that the instruction was to drink before the fizz subsided, possibly because the drug would settle to the bottom of the glass and stick there? I found it such a faff that I asked to change to a normal tablet, which they did with no question, and it has been fine.

SueYoung profile image
SueYoung

I take the soluble type just after eating my breakfast. I swallow it whole with a glass of water the same as I would an enteric coated one. My pharmacist advised that it doesn’t need to be dissolved. I have had no digestive issues.

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