aspirin

[ChillyAsh34]

does anyone on here use gastric coated aspirin I have just read it not very efficient

[EmeraldA]

Hi, I do. Where did you read this. Thanks!!

[ChillyAsh34 in reply to EmeraldA]

it was a piece from the mayo clinic

[Mwalimu]

I do and have done so for about 6 years now. However, I take it 'within' (not before or after, disappeared. my meal) as I do with HU. Once I started using it, the pains I had experienced immediately after taking it. Sallie

[Mwalimu in reply to Mwalimu]

Correction to above!

However, I take it 'within' (not before or after, my meal) as I do with HU. Once I started using it, the pains I had experienced immediately after taking it disappeared. Sallie

[ChillyAsh34]

thank you I have taken it for for almost 2 yrs no problems was just concerned by the article saying it wasn’t as effective as normal ones my hemetologist didn’t say anything when I said I was changing as normal gave me acid

[Superwoman]

yes I have for many years, along with Hydroxy bloods are all stable

[AndyT]

Yes - I’ve taken it for about 15 years, as I don’t like the idea of using regular aspirin for decades.

I’ve seen some reports that it may be less effective, as the coating may prevent some of the aspirin being absorbed, but judging by the way I bleed profusely from the smallest cut, enough seems to be getting through!

[hunter5582]

I have taken enteric aspirin for about 30 years. It does effectively control microvascular symptoms associated with the the MPN I experience. I have tried the Vazalore version of aspirin, but it was much more expensive and I could not tell any difference. I also have used the chewable version, at 40.5mg. Again no difference noted.

My experience is that it is essential to use something to control microvascular symptoms and reduce the risk of thrombosis. Aspirin is no different than any other treatment option we use to manage MPNs. We all respond differently. We all need an individualized treatment plan.

[EdwinaJ]

I have been taking it for over two years and nobody has said to me that it isn't as effective. Should I be changing?

[mark382]

I've been using it for 15 years and no problem. If I cut myself I bleed a lot before it stops, as the local garden centre can testify as i tried closing a gardening knife and it was spring loaded and snapped on my finger. I was originally on the dissolvable one, but gave me pains in the stomach, so my GP put me on enteric coated. Yes it says avoid antacids 2 hours before and after taking. I believe some antacids, especially older ones contaii aluminium and this can bind to the coating and so it doesn't work as well.

[ChillyAsh34]

thank you mark

[Bigcheat]

I have taken 100mg a day for three years now. It works. I used to have migraine with aura every month and visual disturbances whenever jogging. Just a couple of migraines during three years and visual disturbances are gone.

Br,

Bigcheat

[Amethist]

Enteric coated aspirin had absolutely no effect on me, so I changed to regular aspirin. As per my MPN specialists advice, I just take half of one regular aspirin every third day, and that works fine for me.

[Stephen399b]

I have ET, diagnosed over 6 years ago. I did take enteric asprin for about 3 years and it did seem to work. However, despite the coating, I was getting severe stomach pains and cameras 'up and down' indicated some ulceration.

I switched to clopidogrel about 3 years ago and this also works well with no side effects.

Best wishes

[Mishie14]

I started taking nightly coated 81 low dose aspirin pill and within days had to stop. It greatly upset my stomach. It hurt. Had enough pain already from first ET drug Hydroxyurea. My cardio doctor put me on a liquid capsule alternative, in US called Vazalore, and no reaction other than what is expected for my ET condition. Does not require taking with or without food. It is more expensive at about US $1 per capsule compared to the pill form but it works very well and so is worth it. I can also take 385 or less dose of Acetaminophen (US Tylenol) with no Vazalore conflicts. Thank you for raising the topic. I will follow up with my medical team to see what they may have to say about the Mayo info.

[Aldebaran25]

I find that surprising because drug regulatory authorities (such as the FDA) would demand bioavailability studies (how much of the active principle reaches the blood stream) to approve changes in formulation. Does your source mention specific evidence?

[ChillyAsh34 in reply to Aldebaran25]

no it was just a small article by the mayo clinic that I happen to see and I wondered if anyone else used coated

[Aldebaran25 in reply to ChillyAsh34]

Is this what you saw? It is on the Mayo Clinic's Daily aspirin therapy: Understand the benefits and risks

"Should you take a coated aspirin?

Coated aspirin is also called enteric-coated aspirin. It is designed to pass through the stomach and not dissolve until it reaches the small intestine. Coated aspirin may be gentler on the stomach and may be appropriate for some people who take a daily aspirin, especially those with a history of gastrointestinal inflammation or ulcers.

But there's no evidence that taking coated aspirin decreases the chance of developing gastrointestinal bleeding. Also, coated aspirin may not work as well as plain aspirin when taken at the time of a possible heart attack. Talk to your health care provider if you're concerned about ways to decrease your bleeding risk."

The part that says that coated aspirin may not work as well as plain refers specifically to the situation of a heart attack.

[Jelbea]

I also read this somewhere. I had been taking the enteric-coated version of aspirin for many years to keep migraines under control (before I was diagnosed with ET). I am not taking ordinary version and feel no difference.

If anyone here finds out anything more about this could you please post it up as I did not know whether to change or not. From memory the article I read stated that the aspirin dissolved in a different place and that the ordinary version was better for ET.

[ciye]

I can't take normal aspirin and was on clopidogrel but ran out of them and bought the coated aspirin which has been fine. Heamo said the aspirin was better if tolerated.

[Jody00]

Hi

Been taking enteric coated aspirin since 2020 has couldn't stomach the normal aspirin then updose to 2 a day in August now back on 1 a day.xx

[Oscarsboy]

Yes I do, no problems, I found the dissolvable ones did not agree with my system.

[junebuggy]

Came across this article- so maybe if coated aspirin not efefctive try the plain one? thieme-connect.com/products...