Aspirin and Lansoprazole

[jodary]

Does everyone who is taking aspirin also take lansoprazole ? I wasn’t prescribed it but asked my GP a few years after I started aspirin and she did prescribe it only after I asked her to. I have had several attempts to take lansoprazole but each time have given it up as it seems to cause me stomach issues. I take the coated aspirin

[Kelly2]

Hi. I have the same question.

[Mardigras in reply to Kelly2]

Hi Kelly, I take it with Clopidogrel. I cannot take aspirin anymore as if I as much as wring out a cloth, my fingers go black. I have no problems now.

Good luck

[SUFCbaldy]

Hi Jodary. I take it with Clopidogrel and don't have any problems

[Brychni]

Hi I take take the gastro enteric aspirin from Boots. 75mg. Never cause me any problems and cheap.

[lizzziep in reply to Brychni]

Even cheaper in Home Bargains! 😁

[Brychni]

Lansoprazole also makes me feel headachy. I too had to ask the question that if the Aspirin from Boots are coated, I don't need the Lansoprazole: finally, after GP googling, actually during my appointment, 🙄 yes, coated means don't have to take a PPI.

[Brychni]

Apologies for staggered reply. Just woken up. Of course my main issue was absorption if also taking the lansoprazole and apparently , according to my GP, it is. Uou have to be careful how anc when they are both taken. The coated aspirin really don't cause me any tummy burning and I know they're being absorbed properly.

Hope that helps 😊

[mark382 in reply to Brychni]

I take Lanzaprozole half hour before breakfast on an empty stomach. Take enteric coated aspirin at night after evening meal. Never had a problem.

[jodary in reply to Brychni]

Hi, one of my concerns was absorption as I also take other medications including thyroxine I would much prefer to not take the PPI as I feel better without it but people have worried me talking about stomach bleeds. Gp don’t believe it will affect thyroxine absorption and say it is practice to prescribe with aspirin.

[Kelly2 in reply to jodary]

Better ask the pharmacist. They sometimes know more!

[kevmince]

The nhs policy seems to be that lansoprazole gets prescribed to us aspirin takers once we turn 50, that's what my Gp computer decided, after I'd been taking 75mg enteric coated aspirin for 20 years due to ET, it doesn't cause me any problems, so I do take it

[jointpain]

Please be aware that PPIs lansoprazole, omeprezole and the like have an adverse effect on your vitamin B12 stores/absorption, which can present with symptoms identical to pernicious anemia. My wife takes B12 supplements to counteract the effects of omeprezole.

[jodary in reply to jointpain]

This is my concern that PPI can cause other issues . I would like to establish if I need it on enteric coated aspirin

[jointpain in reply to jodary]

Ask to have your blood serum B12 checked, if low, and I really mean below 500 it can cause stomach and colon problems, Normal is considered to be between around 170 to 900, but as doctors are really not very interested in PA they will say you're normal even if outside these figures, in Japan you can be considered B12 deficient with levels far higher than in the UK.

[jodary in reply to jointpain]

Thank you I am due to have this checked this week , I know what you mean about their “normal “ I have this issue with my thyroid tests

[Carol0925]

I take prescribed enteric coated Aspirin and absolutely no problems.

[jodary in reply to Carol0925]

And no PPI recommended by dr ?

[Carol0925 in reply to jodary]

No as I requested enteric coated aspirin. If they couldn’t offer EC then yes I would want a PPI.

[jodary in reply to Carol0925]

Very mixed experiences on here , some say no to PPI if you are on EC. Some say yes

[Hydrox]

I take aspirin and emeprezole as lanzoprazole upset my stomach.

[hall2]

Yes I was told to take it by my GPadter many years on just aspirin. I haven’t had any problems.

[jodary in reply to hall2]

Hi do you take coated aspirin ? And are you on any other medication that may be affected by absorption issues ? Thank you

[hall2 in reply to jodary]

Hi yes I take coated aspirin. I’m also on Pegasys for MPN and other medication for other problems. I’m lucky not to have any issues.

[AndyT]

I’ve been taking 75mg coated aspirin daily for 21 years without lansoprazole and have no stomach issues.

Given the low dose of aspirin and the enteric coating it seems unnecessary to take lansoprazole too - only time I have taken it is when prescribed, short term, alongside other NSAIDs such as Naproxen or Diclofenac.

Probably worth reviewing with your doctor and seeing if it’s really necessary for you, especially as it’s causing stomach issues, not preventing them!

[jodary in reply to AndyT]

As always drs seem to have varying opinions on this. I think one point is that hypothyroidism can cause low stomach acid and obviously PPI lowers stomach acid hence the stomach issues. My gp rolled her eyes when I mentioned this . I’ve yet to find a gp that will listen to concerns without that attitude. I always feel like I have to make my own decisions but value the advice on here from people in a similar situation

[Wildwood6]

I take Lansoprazole 30 minutes before breakfast but with Diclofenac twice daily for back pain and arthritis. I can’t take aspirin. No problem with Lansoprazole.

[Flowers1973]

Hi! I only take a 88mg aspirin. I have ET and Jak 2. I have been taking only asprin for five years.

[jodary in reply to Flowers1973]

Hi was it never suggested to you that you should take a PPI such as lansoprazole for stomach protection ?

[Flowers1973 in reply to jodary]

No

[Cassie11]

Am surprised you were not prescribed it initially as its supposed to stop any stomach irritation from taking aspirin. However, if it makes you have stomach ache I should tell your doctor.

[jodary in reply to Cassie11]

Yet so many on here say no if you take enteric coated aspirin ?

[johoho]

Hi Jodary, I take enteric coated aspirin and Lansoprazole. Enteric alone wasn't enough to protect my stomach, I still needed a PPI. I have no side effects with Lansoprazole.

[jodary in reply to johoho]

Hi, so the aspirin caused you stomach problems?

[johoho]

It did yes, thats pretty typical I believe. My GP said, "aspirin is aspirin, eventually it will damage your stomach if you don't protect it". Lansoprazole made me feel better almost immediately.

[Green1988]

My husband has been taking the costed baby aspirin for 2 years and since last month he has been having g discomfort and burning in the stomach. Doctor gave omeprazole for a month which was ok and he stopped aspirin for a couple of weeks however past few days he feels like it’s starting again. He has calr mutation so not sure if he should stay on the aspirin but I feel it’s safer if he does take aspirin with higher platelets.

[Green1988]

sorry I mean coated

[JaK2ET]

When diagnosed with ET early in 2019 I was told that I would have to take low dose (75mg) Aspirin daily for the rest of my life. (It seems that this is also still a requirement even when platelet counts have been brought into the normal range by chemotherapy or immunotherapy.)

Aspirin was something I had not taken for decades because of its "acid stomach" effects. I was also worried about the risk of gastro-intestinal haemorrhage because this was my late mother's actual cause of death (she had Alzheimer's dementia and it is possible that the internal bleeding may have been at least partly a side effect of her medication for that condition).

In response to these concerns I was prescribed enteric coated Aspirin together with PPI (proton pump inhibitor) Lansoprazole. After about 7 or 8 weeks I began to have bad gut problems, which improved when I stopped the Lansoprazole and started again when I attempted to resume taking it. Around this time I did some reading about PPIs and did not like what I saw. Apparently some people think they should only be used for short-term treatment, no more than a few weeks at a time. When I stopped taking the Lansoprazole I noticed an almost immediate improvement in the "brain fog" symptom as well ...

As a replacement for the PPI I was prescribed Ranitidine, an earlier type of medication for GI protection (H2 antagonist I think); the dose was twice a day, morning and evening/night . To my surprise I soon (after about 4 or 5 weeks) had another bout of gut trouble and again stopped taking all medication. Eventually my haematologist suggested that I try taking the Ranitidine again but just one at night ... and this seemed to work. I was able to continue until Ranitidine was withdrawn from the market generally and I was switched to another H2 antagonist, Famotidine, which I am still taking now (one at night).

I try to ensure that there is a gap of at least 2 or 3 hours between having any food and taking the Famotidine. My enteric coated low dose Aspirin is taken just after a stodgy breakfast/brunch type meal. I do not know if this is the best regime but I can just about manage it (despite sometimes feeling a bit queasy - though that might also be a side effect of my PEG-Interferon immunotherapy).

A highly qualified doctor who is a family member pointed out that the enteric coating on the low dose Aspirin protects the stomach to some extent but there is still a risk of damage lower down the GI tract when the medication is used long term. He suggested that Clopidogrel might be less risky than Aspirin.

Sorry for this long post but I hope that some of it is of interest.

Good luck in finding a medication and regime that suits you!

[Fairydust1111]

I take both and have no problems