Edoscopy Results ; Anyone share their experience or advice please?

[Threelions]

I’m ET J2+ & have been on peg & daily asprin since diagnosis c 4 years ago (also take statins & perindopril)

I had been suffering from excessive heartburn & stomach/chest pain in the last 12 mths + & MPN team referred me for an endoscopy.

Results confirmed Reflux Oesophagitis & Erosive Pan Gastritis.

Appreciate it’s maybe not connected to MPN but wondered if anyone else has suffered with this & maybe if my regular MPN medication may have contributed to it ?

I’ve been prescribed PPI & anti H2 so hope they will sort it out & not interfere with my regular MPN medication.

In all honesty these oesophageal issues have been far worse than any ET symptoms I’ve experienced.

Thanks to my lovely fellow MPNers in advance for any info/experience sharing👍 x

[Cat1001954]

I’m on lanszoprozole and take hydroxycabamide no problems it’s a relief from bad reflux

[Threelions in reply to Cat1001954]

Thanks Cat,

Really appreciate it. 👍

[Cat1001954 in reply to Threelions]

Your very welcome

[hunter5582]

I also have GERD, a Hiatal Hernia, and periodic issues with esophagitis. I have been on a PPI for many years. While not directly related to the MPN, there is a central theme of inflammation. The JAK2 mutation causes an increase in inflammatory cytokines. This can contribute to a variety of symptoms and has the potential to make "unrelated" conditions worse. The injury caused by the reflux can also trigger reactive thrombocytosis. While the GERD and MPN are caused by different things, they have the capacity to interact with each other. Our bodies are integrated systems. This is part of why holistic care is so important.

It is possible that the aspirin and Pegasys may impact the symptoms you report. Pegasys can cause nausea and vomiting. Aspirin is well known for its potential for GI irritation. This would be an issue best discussed with your MPN Specialist.

Wishing you all the best.

[Threelions in reply to hunter5582]

Hi Hunter,

Sorry that you suffer from those issues but most grateful, as always, to you for sharing your experience(s) & some of your wealth of information & knowledge.

Whilst writing, I think I speak for every one of us in this group, in offering you sincere thanks for the time & effort you put into responding to our qs & worries.

You really are the foundation rock of this group & we’re all very grateful to you. Xxx