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New Targeted therapies for MPN

Manouche profile image
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« This article will discuss some of the advances in the targeted therapy in this field in recent years and explore in greater detail some of the most advanced emerging agents as well as those with greatest potential. »

link.springer.com/article/1...

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Manouche profile image
Manouche
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EmeraldA profile image
EmeraldA

Thanks for posting. I will look forward to reading this!

Winterella profile image
Winterella

The ruxo drug doesn’t sound promising, the latter part is more intriguing.

I personally would have likes to investigate more about CRISPR which is base editing = could fix all mutation and cure disease. They already have a few successes with it!

Manouche profile image
Manouche in reply to Winterella

Bi or tri therapy associated with ruxo could be promising.

There’s also DUSP1 as a potential therapeutic target for PV:

nature.com/articles/s41388-...

Manouche profile image
Manouche in reply to Winterella

There’s now base editing + prime editing to repair our genetic mutations in the future. Fascinating field!

statnews.com/2019/11/06/que...

Manouche profile image
Manouche in reply to Winterella

Three people with inherited diseases successfully treated with CRISPR

Read more: newscientist.com/article/22...

Winterella profile image
Winterella in reply to Manouche

This is amazing!! When will mpn’s turn be for a cure !!!

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