New Targeted therapies for MPN

[Manouche]

« This article will discuss some of the advances in the targeted therapy in this field in recent years and explore in greater detail some of the most advanced emerging agents as well as those with greatest potential. »

link.springer.com/article/1...

[EmeraldA]

Thanks for posting. I will look forward to reading this!

[Winterella]

The ruxo drug doesn’t sound promising, the latter part is more intriguing.

I personally would have likes to investigate more about CRISPR which is base editing = could fix all mutation and cure disease. They already have a few successes with it!

[Manouche in reply to Winterella]

Bi or tri therapy associated with ruxo could be promising.

There’s also DUSP1 as a potential therapeutic target for PV:

nature.com/articles/s41388-...

[Manouche in reply to Winterella]

There’s now base editing + prime editing to repair our genetic mutations in the future. Fascinating field!

statnews.com/2019/11/06/que...

[Manouche in reply to Winterella]

Three people with inherited diseases successfully treated with CRISPR

Read more: newscientist.com/article/22...

[Winterella in reply to Manouche]

This is amazing!! When will mpn’s turn be for a cure !!!