Dopamine Receptor-targeting Drugs for New Dopamine-related Therapies for Fibrosis

[socrates_8]

Post by MPN-MATE Admin » Wed Oct 30, 2019 11:37 pm

Hey everyone...

This new piece of Research into Fibrosis may hold some fascinating insights in time... At this early juncture, it is only based upon 'Mouse-modelling' however, it really does make for an interesting read, and I hope that some of you might find it as fascinating as do I...

Best wishes

Steve

mpn-mate.com/forum/viewtopi...

[Aneliv9]

Indeed interesting article. But it doesn't mention anything about MF ( dopamine receptors)

[socrates_8 in reply to Aneliv9]

Hey Aneliv...

Myelofibrosis, is a type of Fibrosis, and the article is about how Dopamine might in time prevent, Fibrosis...

Fibrosis is the formation of excess fibrous connective tissue in an organ or tissue in a reparative or reactive process. This can be a reactive, benign, or in a pathological state. In response to injury, Fibrosis is called scarring...

This is an early piece of research however, and as yet is only being tested in mouse modelling... So it's really just a glimpse of one hypothesis at this juncture...

Promising none the less, in my view...

Best

Steve

[Meatloaf9 in reply to socrates_8]

Thank you for sharing this article. Interesting, probably a long way off. Thanks again.

[socrates_8 in reply to Meatloaf9]

Hey Meatloaf...

Who knows when?

However... all big things start from small beginnings...

Best

Steve

[Aneliv9 in reply to socrates_8]

But if i know well, this new treatment for preventing fibrosis,will not be the first in his class.. Prm151 is supposed to do the same thing in the future.. Or this treatment has something unique that I miss out??

[socrates_8 in reply to Aneliv9]

Morning Aneliv...

Not sure what 'Prm151' does as I have not yet read up on anything to do with it & MF of late. I did hear it was a new trial drug that showed some promise etc...

However, I wasn't trying to make a comparison with any other drug/s or treatments, merely showing a piece of new scientific research that might someday assist MF sufferers is all...

Best

Steve