When to take extra Hydroxy dose: Hi good people. I... - MPN Voice

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When to take extra Hydroxy dose

Ebot profile image
Ebot
23 Replies

Hi good people. I need to take an extra dose of Hydroxy each week. So one day a week I should take 1000mg instead of 500mg. From experience is it best to split the dose am and pm or just take two capsules together? All advice gratefully received. Many thanks.

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Ebot profile image
Ebot
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23 Replies
Swede profile image
Swede

Hi there,

I take one tab, in th morning and one at night, just because I started to take them both at the same time but my stomach started a riot! I also take Kefir with every dose so it now works just fine! Hope you wont have any problems!

Ebot profile image
Ebot in reply to Swede

Thank you! Have a great weekend.

Swede profile image
Swede in reply to Ebot

Thank you and I sure will! I can watch Icehockey online (world championship) You too have a good weekend!

bordeauxgirl profile image
bordeauxgirl

Hi Ebot, I too take double Hydroxy at the weekends making it 1,000mg for two days. I do find it best to take the tablets apart with a meal or sandwich to protect your stomach , I have been doing it for three years and it works. Good Luck and good health. June

Ebot profile image
Ebot

Current opinion seems to trend towards split doses! (OK, two responses!). Yes, I thought it might be better to spread the load. Thank you for replying.

ChrisAnnSen profile image
ChrisAnnSen

I take 10 tabs a week and it never occurred to me to take the double dose separately. I take them after my evening meal, as I do the single dose. No apparent side-effects.

Ebot profile image
Ebot in reply to ChrisAnnSen

Thanks. With Judy's reply we're about even then! Well I planned to take them today so clearly I will now be taking them tonight in one dose! Thought about this a bit late in the day! Hopefully will continue with no side effects. Full on weekend ahead!

piggie50 profile image
piggie50

Hi Ebot,

I take 2 on a Sunday and take them both at the same time. I vaguely remember about 3 years ago my heam saying it was fine to take them together.

Have a good weekend

Judy x

Ebot profile image
Ebot

Yes the CNS just said entirely up to me how and when I take them. Well by default I'm going to take them together tonight - which is what I intended to do until it suddenly occurred to me earlier that maybe I wasn't supposed to! Enjoy the Bank Holiday weekend.

Jane-r profile image
Jane-r

Hi

I have to take 2 tabs on 2 days and one the other days.

I used to take both on fri and sat at same time but gave me a little tummy toilet trouble. I now take both together fri night and the other double dose together Monday night . All ok.

Good luck

Mica11 profile image
Mica11

I take 1000mg every day and I take them both together upon waking without side effects. I was never told to take them any particular way, after food etc. I guess it depends how your system copes with it. You know yourself best. X

Bridie123 profile image
Bridie123

Hi, I take two tabs after my porridge in the morning followed by lots of water ☺

Wyebird profile image
Wyebird

I take mine all to gether. 2 a day 3 Friday Saturday and Sunday. I asked pharmacist exactly the same question she said it’s ok to split them.

You must just decide on a routine that suits you.

X

stillkicking profile image
stillkicking

I take HU after lunch each day. My current regime is one capsule one day and two the next. I take both capsules at the same time on the two capsule day with no problems (other than a nasty battle I had for 10 days with mouth ulcers when my dose was upped from one a day). I do find that I cope better with HU with lunch rather than at night. I think gravity must help get it through the system without it lingering too long in the tum!

Good Luck! :-)

Superwoman profile image
Superwoman

Hi Ebot, I take 500 mg daily and a thousand Sat and Sun, take after my breakfast, have been doing this five years now and so far so good. I sometimes get an upset tummy, but cannot be sure if it is the Hydroxy as I have tried splitting to one in the evening after my dinner and it made no difference, so now pop them after breakfast and all is fine. Still get the occasional upset tum, but I do have to take other tablets so it could be one of them, as the side effects can also cause this problem.

Hope you are doing OK.

Jean

Roger41 profile image
Roger41

Hi, Roger 41( Annemarie ) here ,on September I started on one per week, then two.

As I take a few other pills, I take my two at two pm.

I find that this means I pop pills every four hours.

This suits me.

I still need to put my feet up occasionally for an hour , but I don't mind as I am retired and my hubby is understanding.

Been for my three monthly church.

Nil of note to report.

Had a hospital overnight due to Acute left sided and I pain that caused me to vomit, had every test going including ast bloods which were not great.

Had bruises for two weeks.

But I am still here.

Thank God nothing to report like Alden problems but doctor K wants me to keep an eye on symptoms, query the clot word, not that I am alarmed or worried.

Pain is intermittent, but it has left me with a reduced appetite.

Small portions only.

So......... let's see how this goes.

I have been diagnosed with et with no add ons, since diagnosis, feel no different and tolerating all my meds. I have type two Diabetis, I drink water like,a cammel, do my exercise three times a week, walk 5k once a week and go on holidays.

I count my lucky stars that presently I have a goal to work towards my 65th birthday in December.

I want my pension.

Hope this encourages those that have been recently diagnosed that there is life after and you can be as you wish unicorn or otherwise.

Unicorns are rare and so are we.

Mal42 profile image
Mal42

Hiya, it looks like you can take your pick of when to take hydroxy. I take 10 a week, I take in the evenings, with 2 at the same time on tues, thurs and sunday. I have other meds in the morning, I've been fine, but we are all so different. good luck. Do drink loads of water.

mal

nivana profile image
nivana

I take double hydroxy 3 days a week - take them both after a meal. Don't have any problems with this. Kind regards

Anneian profile image
Anneian

I take hydroxy 500mg Monday-thus day and 1000mg for the other 3 days before I go to bed. Have had no problems. As I take thyroxine in the morning I wanted to ensure I split taking tablets morning and evening.

forwardocho profile image
forwardocho

I take 1,500mgs and I take them altogether at night before or after my evening meal.

WileyFrench profile image
WileyFrench

You’ve had loads of replies but just thought I’d add mine: saw my haemo yesterday and asked him about timing of taking two hydroxy pills on one day and he said it totally didn’t matter. Didn’t need to split them up, didn’t matter if with or after food. So, it appears it’s all what will work best for you!

sinb profile image
sinb

I began taking the hydroxyurea 500mg daily for first 2 wks and Hb. crit and platelets all dropped far below normal. Too low, so had to stop it for 2 wks, then tested again. The numbers ramped up so had to begin again taking 500 mg every 3 days. Now, it's alternate days only in PM, and get tested at 2-3 wk intervals. Symptoms of itching has reduced, but about every 7-10 days a cytokine storm seems to happen causing a full blown whole body itching and hyperirritability. It can last up to an hour. I would take a benedryl for relief but now have been taking 5000mg of modified citrus pectin (powder form) which seems to work rather quickly.

Plavers profile image
Plavers

I take my two tablets of Hydroxy at the weekend together at night with a drink of water and don’t have a problem.

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