The major effect my MPN has on me beside fatigue is itching. I have itched since before first diagnosis in 1994. Have tried so many drugs . Numerous anti-histamines, cimetidine, paroxetine, steroids ,thalidomide, interferon ( made it worse). The only thing that helped was very large doses of PUVA but had to stop as after about 18 months was getting up to max lifetime dose due to skin cancer risk. Hate that I usually go most days OK till bedtime but better than before in initial diagnosis when a shower made me unable to sit still and read the paper over breakfast.
I don't expect any positive replies, nor do I want sympathy but if anyone has a positive suggestion it would be welcomed.
i enjoy exercise and don't mind feeling tired after eg 12 mile walks or 30 mile bike rides but don't find exhaustion helps , just makes itching worse and sleep more elusive. Doesn't stop me getting out and about though.
Don't expect a positive response but as my Dr's have no ideas thought i would ask all of you.