Diagnosed with ET Oct. 2011 and been on Hu ever since different dosages. I am doing well and now my dosage is reduced to 1gr. one day and rest week days 500mg. I am also on 75mg aspirin and Bisoprolol 1.25mg a day. My platelets are under control. Hu side effects are anxiety, fatigue, restlessness, chemo brain, luck of memory, and the worse one is pain in my joints, bones, muscles. Hu affected my R hip joint to the point that I am having problem of walking and have to use crutch. I am considering to change to Interferon and have spoken to a pharmacist trained to work with MPD's that saw me last time I had my regular check up, which was last week. She gave me booklet on interferon information and that she will talk to Dr. Harrison. I need support to make informed decision and to change to interferon but not sure which one it would be better for me. I am hoping to be able to help heal my hip joint after I get off Hu that is constantly attaching it. Thank you and wishing you all well.