I have been ill for around four years. Symptoms include joint and muscle pain, migraines, fatigue, cognitive difficulties, hair loss, burning shins with hair loss, pleurisy twice, arthritis in hands (confirmed dx) wrist pain, hip pain, very bad leg pain especially at night, v. slight redness over nose (like have caught the sun), muscle weakness, shortness of breath on occasions, carpal tunnel in hand (operated on), blurred vision, personality changes (irritability among them). After all these symptoms (of which there are more) I asked my gp to do a ANA test. It came back positive (the only one among many I have had). I finally thought I was getting somewhere. I was referred to rheumatologist who specialises in Lupus. For the first time I felt I was being listened to. He took bloods, ordered lung function tests, eye tests, was checking a recent MRI and echocardiogram (he heard a heart murmur) that I had done when I was referred to the TIA clinic (though now of course I know it was a migraine). I went back this week only for him to say my ANA test is now negative and he has referred me back to the GP - I don't know what to do next.