Hydroxychloroquine

[Biddy47]

I take Hydroxychloroquine 200 one a day in the morning, I have been suffering from on going nausea and my GP thinks Hydroxychloroquine is the culprit, even though I've been taking it for 4 yrs. I take Zentiva brand. Is it ok to take it in the evening? I always take it with food.

[JodieBelll]

Hey, definitely have it right after a decent sized meal and if you can get omeprazole, try that for a few weeks. I actually needed omep at the start but not anymore. Do you have low blood pressure normally? I find that my low pressure contributes to the nausea I get from meds

[Biddy47 in reply to JodieBelll]

Thanks Jodie, I always take it with a meal. I have High BP and also atrial tachycardia and take two tablets for those conditions wich I take at the same time as the Hydroxychloroquine. I just wondered if perhaps I should separate them and take the Hydroxychloroquine in the evening to see if that would help. I had a camera into my stomach last year and everything was fine.

[Biddy47]

Thanks I used to take omeprazole many years ago but stopped taking it as I was told it is only meant for short term use.

[NeuronerdDoaty in reply to Biddy47]

It causes osteoporosis used long term.

[miccika1]

Why dont you try taking half a pill in the mornings and half in the evening? That would be easier on your body and also produce a more even concentration in your body. Most people take two times a day i think. I at least take two times 200.

[Biddy47 in reply to miccika1]

Thanks miccika that's an idea.

[Angiedj]

I found that it caused terrible stomach cramps if I took in the morning. I now take at night & all seems fine

[Biddy47 in reply to Angiedj]

Thanks Angiedj. Do you take it with dinner or bedtime?

[Angiedj in reply to Biddy47]

I take it between 2100-2300 with some biscuits or such like. Hope it helps 😉

[Wendy39]

Hello

I had problems with a very noisey gurlging tummy when I started this but it settled down quite quickly.

I take 200mg in the morning and 200mg at night.

If I don't take with food, I take with a small glass of milk.

I do however insist on the Zentiva brand.

Quinoric made me poo my pants..... TMI??

I also take Ranitidine to protect my stomach.

I hope you get this sorted out.

Wendy x

[Biddy47 in reply to Wendy39]

Thanks Wendy, I always take it with food. Is Ranitidine over the counter?

[Wendy39 in reply to Biddy47]

Hello again.

No, it was prescribed. 150mg tablets. I think most over the counter are 75mg? If I run out I buy them over the counter.

I had a terrible chest pain incident when I thought I was dying and might need an ambulance. GP prescribed it. When I looked through my notes, (my lupus care locally has been terrible and I complained) it appears that an ENT had recommended a stomach protector for possible silent reflux about 4 years before and it has been ignored. Because I hadn't had a copy of the ENT's letter, I hadn't known to ask.

I then found out that a lot of people here take stomach protectors when started on lupus meds.

I take one batch of tablets AM - hydroxychloroquine, MMF, mepacrine, anti-histamine in the moring.

Lunch time - ranitidine (I guess if you take this within 2 hours of other meds, that your medications wont be properly absorbed?

Before bed - hydroxychloroquine, MMF, different anti-histamine and amitriptyline

Hope that helps.

Wendy x

[Biddy47 in reply to Wendy39]

Can I ask those of you who take ranitidine or omeprazole when you take them, do you have to wait some time after taking Hydroxychloroquine to take them.

[Biddy47 in reply to Biddy47]

Thanks Wendy, just sent another message and I think that you have just answered it, about leaving time between meds. What a fright you must have had when you had the chest pain incident. Thanks again for replying to my questions.

[Krazykat26]

I take hydroxy twice a day..at first I found it caused heartburn n nausea so decided the best way to take it was with goats milk.

I'm surprised though that you've been on it for 4yrs n haven't had any problem but recently u have been experiencing nausea.. GP thinks u might have suddenly developed this symptom? Seems unusual to start experiencing side effects after 4yrs?

If it's causing nausea n you're thinking of taking it in the evening u might have some probs in the night..how about taking it midday-ish? Xx

[Biddy47 in reply to Krazykat26]

Krazykat26 I have had stomach problems for years off and on but I have IBS and put the nausea down to that. I follow the low Fodmap diet and have had all sorts of tests which haven't shown anything, so I'm at a loss as to what it could be. I have also on occasions when I've thrown up and it's all really getting me down. Thanks for your reply.

[NeuronerdDoaty in reply to Biddy47]

I threw up too sometimes.

[Sfigata]

Be careful with the Plaquenil. nearly made me blind

[NeuronerdDoaty]

I took 200 in the morning for years. When they added 100 at night the nausea started. I take ranitidine with it. I still have some trouble. I never thought about it being plaquenil. The mornings ranitidine helps.

[GloomyEeyore]

I take one tablet with lunch, one with dinner. I eat half my meal, take my tablet then finish my meal. Haven’t had any problems taking them this way.

[Biddy47 in reply to GloomyEeyore]

Yes that's what I do, take in the middle of a meal, thanks. I don't even know if it's the cause of my nausea but I thought I'd give it a try. Thanks.

[Biddy47]

Phillipo, that's why I stopped taking them and our GP only prescribes them short term.