I have pretty horrid Sjorgrens and they think they're some lupus in there too. I have been on hydroxy 400 for some time now with steroids here and there, but rheumy recently said I should reduce to 200 for a while (can't remember why). She also said that I should think about methatroxate, Alizi....or another immunosuppressant. I've had a look, and none of them feel like very attractive options..and the side effects don't look great! They have just offered me screening for a trial of the rituximab/belimibub combination. She said that often when just taking one of them, the body can work the drug out, bug taking both as a combo seems to confuse the it! Obviously this is a trial, so I might get one or none or both, but just wondered if anyone had any experience of trials and whether it might be worth the risk.
I would be grateful for any thoughts.