Hi my husband has been diagnosed with Lupus nephritis class 3 after a kidney biopsy last month. His creatinine levels as he started his meds were down to 130 from 168. Since starting his meds cellcept 2g and prednisone 20mg his creatinine levels have gone upwards, so has just done IV steroids for 3 days and tomorrow begins 60mg prednisone. His creatinine today was up to 335! We don’t understand why it is going up ? Any ideas ?