Methotrexate : So Tuesday was the first day for me... - LUPUS UK

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Methotrexate

Athens94 profile image
15 Replies

So Tuesday was the first day for me having the Methotrexate injection instead of the tablets. Not going to lie, I was absolutely terrified but I put on a brave face because I know it's for the best.

Words cannot describe how amazing it feels to wake up on a Wednesday and Thursday morning and not feel nauseous. I feel totally fine, no methotrexate hangover, I could get used to this!

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Athens94 profile image
Athens94
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15 Replies
Jacki08 profile image
Jacki08

That's fab news--- 😊

Ianrussell69 profile image
Ianrussell69

Brill the methatrexate hangovers are very bad and people seem to think you put it on but they are truly bad I've been on the injections for about 3/4 months and only had one hangover but I was bad the week befor with joint and muscle pain and also had the fatigue back so it was probably just a bad week !! Glad you feal better on the injection

Athens94 profile image
Athens94 in reply toIanrussell69

thank you :) do you find the injection stings/nips for around 5 minutes afterwards? this is my only negative as it can be quite painful

Ianrussell69 profile image
Ianrussell69

As yet I've not felt the needle and only now and again had it sting but don't rub it I have and it bruised quite bad then the wife said she told you not to rub it ! Only dab the methatrexate spill off glad you are getting on ok

Athens94 profile image
Athens94 in reply toIanrussell69

Yeah I don't feel the needle itself, it just seems to be when I remove the needle it starts to hurt and hurts for the next 5 minutes or so. Thanks for the help :)

jennyall12 profile image
jennyall12

Congrats! May I ask what you need MTX for? Have you tried other drugs? : )

Athens94 profile image
Athens94 in reply tojennyall12

thanks! I use methotrexate for my Lupus. I've been on Hydroxychloroquine for over a year and was having no results with it, also tried half a dozen creams to try clearing up my skin with no success so this was the next thing my dermatologist suggested trying

jennyall12 profile image
jennyall12

Oh ok ... is your lupus just related to the skin?

Athens94 profile image
Athens94 in reply tojennyall12

it is mostly my skin just now. I do suffer from fatigue a lot of the time and sometimes my joints can give me bother but overall I get off lightly compared to others

jennyall12 profile image
jennyall12

Did they diagnose you with a biopsy?

Athens94 profile image
Athens94 in reply tojennyall12

Yeah I had a biopsy and a load of blood tests done

jennyall12 profile image
jennyall12

Aww okay, I was also diagnosed with SLE via a skin biopsy ... maybe you just have discoid lupus and not SLE? : )

Athens94 profile image
Athens94 in reply tojennyall12

Yeah that is possible. SLE is always written on any medical forms I have seen but we're learning new things all the time and discovering new symptoms so it could change.

jennyall12 profile image
jennyall12

Aw ok... plaqunil didnt help at all? How often do you get blood work done?

Athens94 profile image
Athens94 in reply tojennyall12

The Hydroxychloroquine helped for a couple of weeks when I first started it on 20mg. He then raised it to 20 one day and 40 the next with no effect. Then we tried 40mg every day which also didn't make a difference so we tried 40mg one day and 60mg the next which didn't have any effect either.

That's when he started me on the MTX with 40mg Hydroxy daily.

I get my blood work done every 12 weeks just now.

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