LUPUS UK
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Methotrexate

So Tuesday was the first day for me having the Methotrexate injection instead of the tablets. Not going to lie, I was absolutely terrified but I put on a brave face because I know it's for the best.

Words cannot describe how amazing it feels to wake up on a Wednesday and Thursday morning and not feel nauseous. I feel totally fine, no methotrexate hangover, I could get used to this!

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That's fab news--- 😊

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Brill the methatrexate hangovers are very bad and people seem to think you put it on but they are truly bad I've been on the injections for about 3/4 months and only had one hangover but I was bad the week befor with joint and muscle pain and also had the fatigue back so it was probably just a bad week !! Glad you feal better on the injection

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thank you :) do you find the injection stings/nips for around 5 minutes afterwards? this is my only negative as it can be quite painful

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As yet I've not felt the needle and only now and again had it sting but don't rub it I have and it bruised quite bad then the wife said she told you not to rub it ! Only dab the methatrexate spill off glad you are getting on ok

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Yeah I don't feel the needle itself, it just seems to be when I remove the needle it starts to hurt and hurts for the next 5 minutes or so. Thanks for the help :)

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Congrats! May I ask what you need MTX for? Have you tried other drugs? : )

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thanks! I use methotrexate for my Lupus. I've been on Hydroxychloroquine for over a year and was having no results with it, also tried half a dozen creams to try clearing up my skin with no success so this was the next thing my dermatologist suggested trying

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Oh ok ... is your lupus just related to the skin?

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it is mostly my skin just now. I do suffer from fatigue a lot of the time and sometimes my joints can give me bother but overall I get off lightly compared to others

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Did they diagnose you with a biopsy?

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Yeah I had a biopsy and a load of blood tests done

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Aww okay, I was also diagnosed with SLE via a skin biopsy ... maybe you just have discoid lupus and not SLE? : )

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Yeah that is possible. SLE is always written on any medical forms I have seen but we're learning new things all the time and discovering new symptoms so it could change.

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Aw ok... plaqunil didnt help at all? How often do you get blood work done?

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The Hydroxychloroquine helped for a couple of weeks when I first started it on 20mg. He then raised it to 20 one day and 40 the next with no effect. Then we tried 40mg every day which also didn't make a difference so we tried 40mg one day and 60mg the next which didn't have any effect either.

That's when he started me on the MTX with 40mg Hydroxy daily.

I get my blood work done every 12 weeks just now.

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