Amoxicillin with lupus: Hi everyone, I would like... - LUPUS UK

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Amoxicillin with lupus

lyndyjane24 profile image
13 Replies

Hi everyone,

I would like to ask if anyone with Systemic Lupus has been adversely affected by taking amoxicillin (which contains penicillin). I have been taking this drug for over 10 days now and feel it may have caused my lupus to flare. Has anyone else had this experience? Thank you

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lyndyjane24
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13 Replies
MargaretGail profile image
MargaretGail

Amoxicillin is the only antibiotic that I cannot take due to adverse reaction. But I've never considered it to be due to Lupus.

Gailj profile image
Gailj

I can't take anything containing penicillin, that's from childhood, I wonder if it's associated

Kate-L profile image
Kate-L

I became severly allergic to any tablet which contains Penicillin about a year after I was diagnosed with SLE. However, as time as moved on I have become more and more allergic to other antibiotics and now there are only a few I can take safely. This allergy has been put down to SLE as I didn't have it before my diagnosis. Have a word with your Lupus doctors, get their advice and I hope you feel well soon.

Fennella02 profile image
Fennella02

Hi. I developed Lupus after a severe reaction to penicillin some 25 years ago. I was critically ill and my immune system seemed to go berserk. I have read of this being suspected as a causative factor in others. From a different viewpoint, infections (vaccinations and viruses too) invariably trigger a flare in me. Hope you feel better soon. C x

windless22 profile image
windless22

Hi yes can not have penicillin, just few days ago dr changed antibiotics due my infection not healing . 45 minutes after taking doxycyclline.given had reaction fever vomiting prickly rash red face I rang dr a dr on call changed me to cloriflaxin.

Was very ill from doxycyclline.given yet I'd had it before with a photosensitive reaction nothing else.

Im.ok on new one.

Pharmacist had be alerted who checked me over.

Now I often have mini flare with infections.

In fact always as I do at menstrual cycle time month.

Do tell your rheumatologist I shall be documenting as with lupus brain fog im.bound to forget.

Hope you find one that you don't react to.

Hugs

Maddymay65 profile image
Maddymay65 in reply to windless22

I believe doxycycline is contra indicated in lupus , could be cause of flares in some people. Hope you feel better. I too am allergic to penicillin since being a child , will not risk taking it M x

Purpletop profile image
Purpletop

I'm allergic to penicillin so I can't take any of its derivatives, amoxicillin being one of those. But whichever antibiotic I take I feel dreadful while on it and my lupus gets slightly more active for some reason.

I don't have Lupus officially but I have RA and Hashimoto's. I've just had a week on Amoxicillin followed by Clarithromycin for Flu/ Pneumonia. My chest seems to be clear at last but my small fiber neuropathy/ RA seem to be flaring. The doctor blames the flu/ pneumonia for exacerbating my immune system but I am not so sure because I was already in pain and the antibiotics made me feel absolutely awful - especially the Clarithromycin.

lyndyjane24 profile image
lyndyjane24

Thank you for your replies and kind wishes. I will be glad when I finish the antibiotics.

Redtape profile image
Redtape

Amoxicillin is one of the drugs I have had a bad reaction to. I discovered I was allergic to penicillin when I was in my 20s (my father was too) but I didn't realise that my GP had given me something in the same group for an acne-like skin problem. I took a low dose for quite a while before eventually being diagnosed with Lupus. Some years later I found an old leaflet from the pills and it said not to be taken if you have SLE. I was also allergic to Septrin, prescribed before I got Lupus, but my doctor later said that nearly everyone was allergic to that.

I am pretty convinced that my Lupus was sparked by a series of allergic reactions to penicillin-type drugs.

I can use antibiotics but I always make sure the prescribing doctor knows my dodgy medical history and allergic reactions.

Maddymay65 profile image
Maddymay65 in reply to Redtape

I agree I think antibiotics and lupus have to be taken with caution. I have problems with penicillin a horrible reaction to septrin and erythromycin, rash and vomiting. Doxycycline and nitro furoantoin can put me into a flare the latter after 3 doses. It’s interesting but no fun . I try and stay well. Take care hope you do to M x

CatCrzy profile image
CatCrzy

I have just been diagnosed with systemic lupus but have had severe arthritis, especially in my knees, for years. It is very bad. I can barely walk. They want to operate but I am a caregiver to my mother. We don't have any other family so there is no one else to help my mother. Lately, I had been using a walker because my knee got so bad. Then, I had a shot for a lupus rash that had formed on my arm (first rash that actually itched). within a day or two I was walking with just slight pain. I have been on amoxicillin for an ear ache that had occurred at the same time. Each day my arthritis is better. I am scared when I run out of it in twenty days. For me, it has been a total miracle!

Liz2468 profile image
Liz2468

Hi I had taken penicillin for years and then out of the blue I had severe reaction from it my body went into shock and was rushed into hospital this happened not long after my youngest daughter was born so I’m not allowed to get it anymore because off this and it’s flagged up in my medical notes but I wasn’t diagnosed with lupus at this time sorry I couldn’t help you much with your question but wondering if this was the start of my lupus who knows take care

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