Please help. My mum diagnosed with adenocarcinoma may 2015. Inoperable so had concurrent chemo /radiotherapy with cistplatin and vinorelbine. Lung tumour shrinking. March 2016, 2cm brain tumour, treated with stereotactic radiosurgery. Today, diagnosed with 2 new 'spots' in brain plus spread to vertebrae in neck. She is 59, otherwise very healthy, active. Given options of doing nothing, denosumab for bones or chemo (cistplatin again plus pemetrexed) and denosumab. Told may have 12 months with treatment or possibly longer as if responds can go on pemetrexed maintenance. Can anyone give me their experiences or advice.