diagnostic testing for APS... - Hughes Syndrome A...

Hughes Syndrome APS Forum

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diagnostic testing for APS...

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I have blood test every 90 days/per my Rheumatologist. APS and Unspecified Connective Tissue Disorder. Not sure which ones are for APS so I am including all: Any comments? Is evergthing covered?

ANA Titer

Anachoice Cascading Reflex

C- Reactive Protein

Comp. Metabolic Panel

CBC(includes Diff/PLT)

DNA ABS

Cardiolipin Antibody

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paddyandlin profile image
paddyandlin

Hi Luisa,

Welcome to the group. I hope the below helps i am not sure but i will check and see what else i can find

Paddy

The blood tests for Hughes Syndrome have complicated names but are essentially simple and universally available through your doctor/GP. There are two tests – anticardiolipin antibodies and the confusingly named lupus anticoagulant.*

Screening test for Hughes Syndrome

Anticardiolipin Antibodies (aCL) YES sometimes referred to as Antiphospholipid

positive in 80% of cases

higher levels = higher risk of thrombosis

Lupus Anticoagulant (LA) YES Positive in 30-40% of cases

Cannot be used if patient is on warfarin

* The confusing term ‘lupus anticoagulant’ should be done away with. It is NOT a test for Lupus and is NOT an anticoagulant. But it is a historical term, and so far has stuck. Confusion is added to by the variety of clotting tests used in different laboratories with abbreviations including KCT, KCCT, DRVVT and so on. A topic best left to the haematologists.

Of these two tests, the first is far more important and more frequently positive – but because nature can be awkward, some patients have only one or other test positive – hence the need to test for both. Having said this, we do see some patients who appear to have Hughes Syndrome in whom both tests are negative.

in reply topaddyandlin

thank you

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