pBAT update after two cycles. - Fight Prostate Ca...

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pBAT update after two cycles.

KocoPr profile image
10 Replies

I started BAT using testosterone propianate which requires injections every other day during high T cycle. The beauty of that is fast clearing and slamming the jail cell shut on the beast with darolutamide.

My recent PSA came in as 0,05 which is almost at end on my 2nd darolutamide cycle.

My Numbers

DATES 2023

NOTE:

After One Year on ADT/Osterine and cardarine my NADIR= 0.03

July 29 2023 BAT START DATE

July 11 Last day of 1st HIGH T Cycle

uPSA 0.33

T 1808

July 20 9th day into 11 day DARO Cycle

uPSA 0.08

T 24

E2 <15

Aug 10 Last Day of 2nd High T Cycle

uPSA 0.46

E2 <10

Aug 21 11th day of 2nd Daro Cycle (extended Daro cycle 6 days to coordinate High T during my Camping Vacation)

PSA 0.1 (i messed up by not ordering ultra sensitive PSA uPSA

Aug 31 Last day of NEW extended DARO Cycle

uPSA 0.05

T 12

Sep 19 end of third high T cycle:

uPSA 0.64

E2 34 <===climbed dramatically from <10 on last of second high T cycle. This is due to not taking Orgovyx and letrozole (aromatase inhibitor) during this third high T cycle.

I am also using Orgovyx on and off trying to get a gauge of E2 and also during daro cycle my total T levels. Want to keep it in teens or lower.

Also during low T cycles i take 10mg of osterine and 3mg Carderine every day.

Every single CMP and CBCw diff are all in the green.

Will check lipids soon, but i suspect good numbers.

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KocoPr
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Ramp7 profile image
Ramp7

I've been doing pBAT since Jan. Good results with a slight up tick recently. Introduced Nubeqa "Darolutamide". Curious to see hot things progress. Good news for you!

KocoPr profile image
KocoPr in reply toRamp7

Did you get any genetics done recently since you failed zytiga ?

The darolutamide has less mutation failures, and is a very good complement to BAT.

Ramp7 profile image
Ramp7 in reply toKocoPr

They did Genetic tests at Dana Farber recently. I have not heard back yet on results.

KocoPr profile image
KocoPr in reply toRamp7

Excellent! Your in good hands at DF

Ramp7 profile image
Ramp7

Dana Farber is great but they are not really assisting with BAT. Dr. Beltran is a close colleague of Dr. Denmeade who I sought out before embarking on BAT. But she is part of the Team but not active. My local MO once he saw that I was indeed a responder is assisting. He wrote the script for Nubeqa. I obtain my own Propionate Testosterone and administer in a similar fashion as yourself.

PCaWarrior profile image
PCaWarrior

Today I did a crude androgenic calculation for Rad-140. I've seen ratios for Ostarine, Rad, etc. But no raw numbers. So, it's a big guess if these apply to Ostarine. Odds are that they are even more stringent for Ostarine.

Anyway, to cut it, 10 mg of Rad-140 looks to have roughly the equivalent androgenic action of 180 ng/dl of testosterone. 1 mg should be relatively safe. If we assume a 10:1 anabolic to androgenic ratio, we get 1800 ng/dl equivalent anabolic action if 10 mg of a SARM is used. Rad-140 "supposedly" has a 90:1 ratio. I've always doubted this. If it really was that anabolic we would be competing for Mr. Olympia.

That number is from my experiments and might not apply to others. I've had the data over a year but just got round to calculating serum levels for various substances (and splitting out androgenic and anabolic if applicable). I found some study Cmax data for NPP and Deca and the numbers are surprisingly close. Propionate and cypionate are within a few percent. SARMs are harder since I haven't found raw magnitudes. Just ratios.

If 10 mg is working for you, ok. Consider trying less though to see if that makes a difference.

Short half-life so another option is to try 20 mg once a week. I'm trying this now with oxandrolone (100 mg once a week).

Oxandrolone was what got me started with the detailed serum level calcs. I was taking 25 mg a day. Felt great. But as it turned out, my androgenic levels weren't very low. So my PSA didn't go down very much from high T.

5 mg every day or 100 mg once a week might work. I'm trying the 100 mg option first.

TN1932 profile image
TN1932

Thanks for the update. I'm glad that you've got good results with BAT.

KocoPr profile image
KocoPr in reply toTN1932

Thank you. I am also glad i started it before drug resistance.

MateoBeach profile image
MateoBeach

Very good results KokoPR. As you know I also do pBAT for the last 4-5 weeks of my 12 week High T cycles. Then Orgovyx one month with Daro the first two weeks of that. Excellent results for me also 2.5 years on modified BAT now.

I use Osterine also twice weekly but only during my high T cycles as it activates the AR similarly to testosterone, so I don't use it during castrate T month, just carderine. I understand RAD-140 is a SARM that does not activate the AR in the same way. So I am wondering if that might be a better choice during the ADT/Daro month? Paul

KocoPr profile image
KocoPr

Thanks for the great info Paul. Do you really need SARM ( Osterine) during high T? I only take the SARMs during castrate phase to mitigate the SE’s. Also very interesting you only do Orgo during low T. I like that you’re high T cycle is 3 months with one month castrate cycle. I would be afraid my PSA would climb to high.

What is your last PSA after high T and after castrate cycle?

No data on SARM use during ADT so it is all n=1s for us.

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