I have only been on Amytriptaline for a few weeks and when I increased the dose I felt less tired after a few days, but then my energy level plummeted. I think this may happen each time I increase the dose, but only time will tell. I have been taking Tramadol for a spinal problem for some time, I have been reducing the dose slowly but it has never had any effect on my fibro pain. However, a couple of nights ago my legs were causing me pain so I took 1 Tramadol and 1 Paracetamol and it reduced the pain enough for me to get to sleep and I slept for 4 hours and then dropped off again for a few hours. It is OK to take these drugs together, I have a friend who is a very experienced pharmacist and he recommended taking them together if the Tramadol were taking time to be effective. I have repeated this several times now and it is helping me sleep, so I shall continue. Perhaps I have found something that will work for me.