Embryo grading

[Emsk14]

Hi, we have just had a failed FET with a 4AB embryo. (Was frozen at 3AB but expanded before transfer) We have 2 4BB embryos (one via IVF & 1 via ICSI) I’m unsure as to whether we try the 4BB embryos or go for a fresh cycle. We have done 2 previous fresh cycles and both times had 5AA embryos, one resulting in the birth of our daughter, the second most likely failed due to fluid in my uterine cavity. Does anyone have any success stories with 4BB embryos or similar situations?

[JA-fnuk Partner Nurse Fertility Network UK]

Just wanted to wish you good luck with your next transfer Hope you get a few replies to your post that help with your decision making

Thinking of you

Janet-Partner

[Emsk14 in reply to JA-fnuk]

Thank you so much x

[Nane22]

hi I’m currently 6and half weeks pregnant with a BB grade embryo. I had treatment in Spain so they only put the letters and no numbers in front.

My previous transfer was a 5AB and I had a BFN.

I think you have a good chance too with your 4BB

Wishing you all the best xx

[Emsk14 in reply to Nane22]

Hi, congratulations on your pregnancy! Thank you for sharing and it’s definitely reassuring to hear x

[Connie290]

Currently 34 weeks with a 4BB 😊 all my higher grade ones failed. Good luck ✨️

[Emsk14 in reply to Connie290]

Congratulations on your pregnancy! Thank you for sharing that’s so reassuring to hear ☺️ x

[Kitkat10]

hi, fairly sure my daughter was a 4BB after two fails with a 5AA and 5AB,

Good luck xx the embryologist told me that they just look at certain characteristics for the grading and that my 4BB was ‘doing all the things it should be, even though it didn’t meet the 5AA appearance criteria. I felt upset when I heard the grading, but I didn’t need to be.

Good luck xx

[Emsk14 in reply to Kitkat10]

Thank you for sharing, that’s really good to hear. It’s hard to not get caught up in the embryo grades when they go by that, but I guess it’s more the chromosomes that matter x

[Kitkat10 in reply to Emsk14]

Yes exactly that, if the genetics are correct then the grading doesn’t mean much at all and vice versa. As frustrating as it is, there is so much still unknown about embryo quality and my embryologist admitted ‘we just don’t really know’ .

Good luck xx

[Emsk14 in reply to Kitkat10]

Yeah and even 5AA & PGT tested embryos can still end up in miscarriage, it’s just such a hard one to call isn’t it. I might see if I can have a call with the embryology team to see what they say. They have said we do still have ‘good’ embryos x

[Doodlebug23]

My BB is currently snoozing on my shoulder! All my prior failures were AA and AB embryos.

[Emsk14 in reply to Doodlebug23]

Ahh how lovely 🥰 thank you for sharing x

[Rxyfxyldy]

Hi! I transferred 2 embryos - 1x 2BB abd 1x 3BC. One of them is my daughter who is wonderful. You've got this!

[Emsk14 in reply to Rxyfxyldy]

That’s so nice to hear, thank you for sharing 🥰 x

[Twiglet2]

A 4BC FET made my perfect son, all the ‘better’ graded embryos either failed to implant or miscarriages. There is no way in the world I would be doing another egg collection with 2x 4BBs sitting waiting as they have every chance to be your miracle. Good luck! Xx

[Emsk14 in reply to Twiglet2]

Thank you so much, that’s so reassuring to hear. Our daughter was a 5AA fresh transfer and I think I just have it in my head that I need that again because it gave us our daughter. We have had x2 5AA embryos in another fresh cycle but they were both put back in when I fluid in the cavity, which was likely to have caused them not to implant. It’s so hard to not get obsessed with embryo grading, but hearing others stories is so reassuring. Thank you for sharing x

[Wannabb20]

Hi, I had a similar dilemma. We made 5 embryos around 4 years ago-the first fresh transfer was a miscarriage (5AB), then our daughter (frozen 5AB), a few years later another miscarriage (frozen 4AA ) and then recently I had 2 x 4BBs left so was debating collecting more but decided just to go for it, the first 2BB transfer resulted in a blighted ovum and then the very last 2BB embryo has worked and currently 18 weeks pregnant 🤞. I should add both 2BB embryos expanded to 4BB on transfer day. Good luck with your decision x

[Emsk14 in reply to Wannabb20]

Hi, thank you so much for sharing a congratulations on your pregnancy ☺️ that’s so reassuring to hear and I guess it really is down to complete luck! I don’t really want to go through another fresh cycle to be honest, but also want to know we still stand a decent chance with our 4BB’s x

[XXKKXX]

Any grade can lead to a pregnancy. Good grades can fail and low grades can work. It's basically just the appearance of the embryo. I did a double transfer with 3cc and 5cb because mine were 'poor quality ' and told me I'd probably need another round or two for success as this transfer was unlikely to work. Well that little 3cc or 5cb is almost 8 months old

[Emsk14 in reply to XXKKXX]

Hi, wow that’s amazing! So amazing to hear stories like yours. And you’re so right, some good graded embryos can still fail and ‘poorer’ one’s be successful. Thank you for sharing x