Donor eggs/embryos and reproductive immunology did you need/do both for success?

[Flora14]

Those of you who finally had success with donor eggs or embryos did you also need a reproductive immunology protocol (eg did you have steroids , hydroxychloroquine, intralipids neupogen, lit treatment anything like that) or did donor option work all by itself???I have had many failed rounds including 3 with immune protocols and still nothing - implantation failure- think I will have to go down donor route but I'm not sure whether to bother with anymore immune stuff.

I can't afford it and it's not working anyway but can I just ignore the "potential issues " that I have...

I'm skeptical about ri anyway but had to try it.

Thanks

[Purple276]

Hi Flora,It's so hard to know what really makes the difference. For us we were suggested to try the immune tests first and that still didnt work so moved to donor eggs and end up taking steroids and inhiza blood thinning injections as well as donor eggs.

Personally I'm not sure the immune helped but you never know and always felt like better to throw eveything at so would prevent feeling like I could have done more.

I ended up doing an ERA which showed I needed fewer days of progesterone before transfer which made sense as I always had really short cycles so think that made the difference for me, but that's my personal experience.

I really hope that a move to donor eggs will work for you and have everything crossed xx

[Boo718 in reply to Purple276]

I would agree with this i did the era too and it said I needed an extra day of progesterone which made sense as I always had long cycles. I think it made the difference for me xxx

[Hidden]

So sorry you find yourself in this position. After six failed fresh cycles we moved to donor and were lucky enough for it to work on our first transfer. I asked my doctor for steroids as I felt it was worth throwing everything at it but his attitude was to not do anything other than progesterone for first DE transfer and see what happened and then add to the next transfer. I was surprised as this was one of these ‘take all the money, bells and whistles’ type London clinic! But turned out he was right and I didn’t need steroids. Shout if any questions. Heaps of luck xx

[minnesota_girl]

Hi Flora,

I included immuno treatment with my donor cycle as it was the recommendation of my clinic in Spain. That included intralipids, steroid, and clexane X

I'm currently 17 weeks pregnant after 4 other cycles and recurrent loss x

[Boo718]

hello I went down the double donor then donor embryo route and I was on clexane aspirin progesterone and prednisolone (steroids) xxx no underlying issues for me it was a ‘just incase’ xxx

[ChloeDE]

Hi, I did one donor transfer without anything extra and miscarried. The next transfer, the consultant suggested adding prednisolone and clexane as a precaution and that transfer was successful.