Down regulation done!: Hi Guys, Just... - Fertility Network UK

Fertility Network UK

56,477 members59,790 posts

Down regulation done!

Melonay1987 profile image
10 Replies

Hi Guys,

Just had my gonapeptyl injection this morning. I'm hoping I dont have too many side effects haha, what side effects did everyone get?

Hope everyone is well xxxx

Written by
Melonay1987 profile image
Melonay1987
To view profiles and participate in discussions please or .
10 Replies
Purpledoggy profile image
Purpledoggy

I'm pretty much at the same point as you - started Bemfola on Tuesday on long protocol, first cycle. So I can't tell you much yet but wanted to wish you lots of luck with your cycle. So far I still seem to have some of the lingering effects of downreg - mainly the insomnia and the odd night sweat, although last night I don't think I had a proper night sweat so fingers crossed that's it! xx

Edit: Just realised that Gonapeptyl is an GnRH agonist, not FSH so not sure of your protocol. I did downreg with buserelin and I got few side effects other than the disturbed sleep and a night sweat or two each night. Maybe slower memory but mine is crap anyway! I wonder if older ladies suffer less (I'm 39) than the young 20-somethings as we have fewer hormones to begin with. xx

Melonay1987 profile image
Melonay1987 in reply toPurpledoggy

Hello, thanks for your reply. I have no idea which meds are which, tbh the clinic hasn't fully explained, but I suppose I've not asked many questions as I'm new to all of this. I've got a baseline scan on 25th and on the 26th I start menopur.

Good luck on your journey, be nice to keep in touch if were along the same schedule xxx

Purpledoggy profile image
Purpledoggy in reply toMelonay1987

Ah OK so it sounds like you're at the start of downreg. I'm a couple of weeks ahead of you as I started downreg on 15th Dec and started my stims Tuesday 29th. If all goes to plan my egg collection is likely 11th Jan ish, though I'm a bit nervous about the COVID situ as I had a test done Tuesday to confirm negative before starting stims and still not had the result back over 3 days later. I have to have another test 3 days before egg collection (so probably next week) and that result must be back within 3 days or they will cancel the cycle. So, kinda shittin bricks over here!! I think I can kind of deal with a cycle being being cancelled because of my own body, but if it gets cancelled because a test result took too long to come back I think I might fall to pieces. Who on earth thought IVF during a pandemic was a good idea ;) xx

Melonay1987 profile image
Melonay1987 in reply toPurpledoggy

Ahhh yes your a little head of me. Gosh tell me about it, this covid situation is a nightmare. My partner got it 2 weeks ago and I felt so selfish because all I could think of was "its going to ruin the ivf" shes fine now but its affected her chest a little. I'm sure your results will be fine, do you have to isolate before egg xollection? Weve been told we have our final scan and swab and then need to isolate before the egg collection. Very strange times. Xx

Purpledoggy profile image
Purpledoggy in reply toMelonay1987

Oh no, I hope she's OK! I can totally understand your feeling that way - my husband works in a hospital (in a research dept working on COVID) and I am getting more and more ansty about him going into work, considering his closest worker just tested positive, thankfully he has not been in contact with him over the last few weeks. I was far more worried about our IVF than the poor guy catching it. I'm not so worried about me being positive as I'm isolating already, although I do worry about hubby bringing it back with him. He's working from home much more which helps. I have to completely isolate for the 3 days between the test and egg collection (which is effectively no different to what I am doing now other than weekly acupunture) so it's just the test being delayed that I am really panicking about now. I'm praying they have ringfenced tests for hospital admissions and am waiting to hear back from the nurses about the current situ and whether I can have a test 4 or 5 days before to allow for longer turnaround times, or if they are in fact sitting on my test result because they are closed today. It's the not knowing that's killing me and probably won't get a reply now until Monday. I just keep telling myself if I manage to get preggo it will be a crazy story to tell one day about that time I did IVF in the worst pandemic since Spanish 'flu. xx

Melonay1987 profile image
Melonay1987 in reply toPurpledoggy

Oh bless you, thats worrying isn't it. im NHS and my partner is a prison officer so I'm always worrying too, so I totally understand. As of IVF isnt worrying enough eh?.....I pray yours goes as smooth as possible. Is your partner allowed in with you at the appointments, mine isn't and bless her she feels left out :(

Purpledoggy profile image
Purpledoggy in reply toMelonay1987

I’m not sure if he is allowed in yet-so far I’ve done all the in-person things on my own but haven’t felt the need to have him there and he hasn’t wanted to (not that he’s not supportive, just very laid back!). So I haven’t asked. I really hope he can be there for transfer though, and of course he’ll have to come in for his ‘contribution’ 😂 That must be so hard your partner can’t be there when she wants to be involved. I really feel for you both. But, right now it’s all very basic biology and sciencey, she will be more involved with your pregnancy and of course everything after, so hopefully that will make up for it. Wishing you a smooth, stress free (and of course successful) IVF! Xx

Melonay1987 profile image
Melonay1987 in reply toPurpledoggy

Ahhh fair enough bless him 🤣 y shes going to be doing my injections so hopefully she will feel more involved. Thank you my lovely, wishing you all the luck in the world xxxx

Fingers crossed for you! I start down reg on Monday xx

Melonay1987 profile image
Melonay1987 in reply toAriel_the_mermaid

Thanks Aerial. Fingers crossed for you too, im new to all this so not sure what all the different meds are. My egg collection is due first week of Feb. Xxx

Not what you're looking for?

You may also like...

down regulation for adenomyosis advice

hey everyone, feeling a bit uncertain after a call with my consultant. After three failed FETs (x2...
Bed12 profile image

Diet during down regulation

Hi everyone, This may be a stupid question but is there a good diet to eat while down regulating?...
Thegirl84 profile image

Down regulation scan

just a quick post with an update. Had my down regulation scan which was all fine. Now I’ve...
Babyblues1 profile image

Down regulation: 1st stage!

Hello everyone, I'm just after some advice. I am on day 10 of my nasal spray and had spotting day...
Lucyloo81 profile image

Bleeding on down regulation?

Hi everyone, this is my first time writing...hope someone might be able to reassure me...I'm on day...
chrissie_81 profile image

Moderation team

See all
Claire_FNUK profile image
Claire_FNUKAdministrator
JA-fnuk profile image
JA-fnukPartner

Content on HealthUnlocked does not replace the relationship between you and doctors or other healthcare professionals nor the advice you receive from them.

Never delay seeking advice or dialling emergency services because of something that you have read on HealthUnlocked.