Low maturity rate & extracellular deb... - Fertility Network UK

Fertility Network UK

56,459 members59,773 posts

Low maturity rate & extracellular debris - confused?

5 Replies

I had EC yesterday, which went ok. Still in a bit of pain, but so glad the injections are over.

Just had Day 1 results and my maturity rate is about 50% - exactly the same as my last failed cycle where we didn’t achieve a single blastocyst.

The doctor put me on a higher dose of Gonal this time and delayed the EC, but my maturity rate is still the same. Apparently maturity rates should be 60% - 80% and mine is below average. Does this indicate poor egg quality? Why did my higher dose/protocol have no impact? What does this mean? I am so scared and confused.

Day 1 report also shows high degree heterogeneous cytoplasm in two eggs and that all oocytes contain extracellular debris. The doctor didn’t really explain what this means. I am meeting him again today to discuss further. Does anyone know? What are the causes? Will this impact embryo development?

I am so scared we won’t get a single blastocyst again. Over the last three months we have done everything: no alcohol, healthy eating, lots of ubiquinol.

The last two weeks on high doses of Gonal and Menopur have been hell - what if it is all for nothing? All that money wasted? My body and mind traumatised for nothing? Why can’t we even get past the first stage?

Life is so cruel 😭

Read more about...
5 Replies
Alpatchino profile image
Alpatchino

Hey Anna,

how are you? How did your little embryos do?

I don’t know the answers to your queries - I hope your chat with the doctor answered them for you and the outcome was positive. I just wanted to show my support. This process can be so cruel. I hope you can be kind to yourself and stay strong. X

in reply to

Thank you x

Scarlett13 profile image
Scarlett13

What did the doctor say? What are those things? How are you feeling now? Hope you’re ok xxx

in reply toScarlett13

He didn’t really say anything helpful. Just shows me some graphs and said it was a minor flaw.

I was too distraught to push him for a straight answer xx

Not what you're looking for?

You may also like...

poor egg maturity and metformin??

Has anyone without PCOS been prescribed metformin and seen an improvement in egg quality in...

Low Blastocyst rate

Hi there I just wondered if anyone has had similar experience in getting low blastocyst rates in...
Kittykat113 profile image

Low fertilisation rate after ICSI - any experiences?

We have male factor infertility - now on our first round, and last week we had 12 eggs collected, 8...
LCharlton profile image

Round 5 💔 need advice on Clinics Abroad & egg maturity issue

Has anyone used any clinics abroad. How much is it? Taking into consideration the flights,...
Chegotsi profile image

Day 13 stimming - feeling awful and discouraged

Day 13 on Gonal f (dose 300). Yesterday’s scan showed follicles are developing really slowly and...
lmno profile image

Moderation team

See all
Claire_FNUK profile image
Claire_FNUKAdministrator
JA-fnuk profile image
JA-fnukPartner

Content on HealthUnlocked does not replace the relationship between you and doctors or other healthcare professionals nor the advice you receive from them.

Never delay seeking advice or dialling emergency services because of something that you have read on HealthUnlocked.