FET use Cetrotide yes or no? - Fertility Network UK

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FET use Cetrotide yes or no?

18 Replies

Hi All. I’ve been asked to participate in a study in my FET cycle where they look at the impact of using Cetrotide (to stop ovulation) in addition to other drugs pre-transfer. The clinic said some clinics do and some don’t use it presently. I’m wondering if it’s commonplace not to use it or do most places use it. Quick poll:

Those who’ve had FET did your clinic use Cetrotide for you?

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18 Replies

No I didn’t use it x

2-shades-of-hope profile image
2-shades-of-hope

Not for me.

Yes mine did

Lojane profile image
Lojane

Cetrotide is an antagonist and is used if there are no natural cycles to suppress. The alternative is Buselerin which is an agonist and acts in a slightly different way. It has to be taken for longer than cetrotide Buselerin is the gold standard and has been used for over 20 years. Is the aim of the study to see if cetrotide is as effective?

in reply toLojane

Some centres use cetrotide to suppress ovulation (as well) whereas others don’t use it at all apparently. The study is to look at whether it’s necessary as well - there’s not been a study in to that. thefertilitypartnership.com...

in reply toLojane

clinicaltrials.gov/ct2/show...

Core profile image
Core

No I didn’t have to xx

MissSaoPaulo profile image
MissSaoPaulo

No, didn't take it

Lou7744 profile image
Lou7744

I didn’t take it either 💕 xx

No I didn’t have it. The progynova on its own was enough to stop me growing a follicle. I would be asking about any potential side effects/benefits/risks before agreeing to have this drug.

Lizzielizzielizzie profile image
Lizzielizzielizzie in reply toLizzielizzielizzie

Ps my clinic said they saw no difference in success rates between fets with down regulation and without, but I think they use buserelin if they do down regulate.

Ruby26 profile image
Ruby26

I had fyremadel (probably not spelt right!) which is supposed to be the same as cetrotide which I had on my fresh cycle. I had the same side effects! X

Kaylon profile image
Kaylon

We used cetrotide with our fresh cycles and buserelin with our FETs. Is cetrotide not safe? Or not tested enough?

Mainecoonfan profile image
Mainecoonfan

I've used cetrotide for both my cycles, which were both fresh with the option for freezing if I had enough developed embryos (which I didn't for my last cycle).

crisps88 profile image
crisps88

We used cetrotide alongside Metiofert for FET. Unsuccessful first ivf x

han6590 profile image
han6590

Hi, yes I used Cetrotide for FET (e-freeze study) for 7 days alongside progynova tablets. The injections need patience (mix a powder and solution) but I didn't have any side effects. First cycle BFN but more frosties to try next month. I think my clinic has changed from Cetrotide to another injection but not sure which.

Thank you all - it’s helpful to have a picture of what others are doing. Xx

everhopeful83 profile image
everhopeful83

No I didn’t have it either xx

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