Fertility Network UK
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Switching from clomid to letrozole?


Just wondering if anyone had been switched from clomid to letrozole? I've been taking clomid 100mg for the last four cycles with day 21 bloods coming back with no sign of ovulation so the consultant I'm under has switched me to letrozole for the next three cycles.

I wasn't told he was changing the meds at my appointment but got a call from the clinic nurse a few days after. I asked what the differences are with the drugs but she didn't know and said she would check and get back to me. That was two weeks ago. I've just been to see the gp for my prescription and he held his hands up saying it's not an area he's entirely familiar with so couldn't explain the differences.

Has anyone else had clomid swapped for letrozole? Or aware of the differences between the two? X

1 Reply

Hi weewinkle. Just saw your post – been away for a few days. Letrozole is a drug that is commonly used to treat estrogen-dependent tumors, particularly breast cancer in older, post-menopausal women. It has also been shown to induce ovulation in women who do not ovulate. For this reason, some infertility specialists are using the drug in women who cannot tolerate or who do not respond well to Clomid. Hope it works for you. Diane


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