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Fertility, Miscarriage & IVF Support
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Vitamin B12 Deficiency & Miscarriage

Just after my first miscarriage last year I was diagnosed with B12 deficiency. Doctor said it was not a factor in the miscarriage. However, I’m currently reading the book ‘It starts with the egg’ which states that ‘a deficiency in B12 causes the amino acid homocysteine to build up in the body, which in turn reduces the number and quality of eggs, and that high homocysteine levels have been linked to high rate of miscarriage’.

Over the last year I have continuously monitored my levels, and paid privately for injections (NHS gave me initial injections but wouldn’t continue injections as, although I was still below the recommended threshold I wasn’t apparently low enough below it to qualify!) thankfully my levels have increased hugely so I’m hoping this helps my egg quality.

I’d be really interested if anyone has any thoughts on B12 being linked to miscarriage or has any success stories once b12 was increased?

6 Replies

Interesting I’ve not heard that something else to look into. I do take a B12 supplement extra to a prenatal, I got them for my partner but I started taking them. I’ve done the 3 mths of dhea ubiquinol pqq zinc royal jelly maca omega 3 fish oil with dha folic acid vits c&d and I still mc my 3rd. Lost hope in supplements.


I'm sorry to hear about your mc. Have nothing of the kind to share. So thank you for this additional info. Am definitely going to reaserch more. Our dr at bio tex says, the risk of miscarriage is about the same for women who go through IVF treatment and those who conceive naturally. risk simply increases with age. It’s important to note that success rates, both pregnancy and live birth, are also affected by the use of donor eggs, infertility, previous treatment outcomes, clinic expertise and more.


Hello I have a under active thyroid and with that comes low iron low b12 and vitamin d issues I supplement with all of them I was also using ovasitol for egg quality and hormonal balance plus magnesium also. I sadly had another miscarriage last week bringing me to a total of three loses I hope my gp will now allow further tests. I'm not sure how much of a role my supplementing took but it didn't seem to help the outcome sorry your going through this heart break too x


I'm so sorry to hear about your mc :( If a miscarriage happens during the first trimester of pregnancy, it's usually caused by problems with the foetus. About 3 in every 4 miscarriages is said to happen during this period.

If a miscarriage happens after the first trimester of pregnancy, it may be the result of underlying health condition in the mother. These late miscarriages may also be caused by an infection around the baby. (It leads to the bag of waters breaking before any pain or bleeding.) Sometimes they can be caused by the neck of the womb opening too soon..Many women who have a miscarriage worry they'll have another if they get pregnant again. But most miscarriages are a one-off event. I've been prego once in my life. But we had to terminate it.. See, I've always been the severe heart disease sufferer..Dr told staright to dh - me or the baby..The worst scenario was both..So we had to move through this heartbreak..

I'm so sorry to hear dear nettiboo1982, you've faced 3..I'm praying for you to get the problem the best nailed soon to keep you away from this nightmare. Take good care Xx


Hi, lovelies. I researched on this point once. My doctor ran a B12 blood test and it came up woefully deficient. I'd had the symptoms for years. BUT I never paid much attention. Wondering whether it could have been the cause of my mc, I found several articles linking B12 deficiency to infertility, miscarriages, birth defects and a host of other health problems. They said like 25% of adults have this deficiency.

I then called my fertility doctor. He said NO. The B12 test is NOT part of the pregnancy loss panel of tests. That's why I never had it. I can't be certain that this is what caused my mc. but I know how desperate it can feel when you don't understand why your body seems to be failing you. Having travelled this road, I certainly felt it was worth coming back here to mention this. Thank you, LittleMermaid1 for starting this thread. Hope you're doing well.


Thanks so much for this information.

So sorry for you loss.

Sending baby dust your way.