Liver stifness

[Realy]

can enlarged liver, elevated ferattin or any other abnormal bloods give a higher KPA score due to those factors. I recently watched a round table discussion about fibroscan and the One dr mentioned if patient has high ferratin than they should be retested when ferratin levels return to normal range? Any thoughts

[nash2 Partner]

High ferritin may suggest iron deposition in the liver which is harmful so should be monitored and retesting is important.

[Realy in reply to nash2]

I think the ferattin should be included by drs running liver tests.

[nash2 Partner in reply to Realy]

personally, I have a full iron panel run quarterly so I agree with you.

[Oldliver in reply to nash2]

I have higher Ferritin... what does that imply for me health wise?

[nash2 Partner]

You should be evaluated for whether or not you are depositing iron in your liver. I have to have phlebotomy about once a year to get rid of excess iron. You have to have iron to make red blood cells so the details can vary quite a bit and a little bit high may mean nothing but very high suggests a disease process.

[Roxanne9 in reply to nash2]

What do you you consider high? My ferritin levels have been in the high 500’s and they are currently 482. I mentioned it to my doctor and although it is high by their lab’s standard he told me not to worry about it. It is not high.

[isi123 in reply to Roxanne9]

Hello, I have a disease called hemochromatosis and one of its indicators is high ferritin levels. In my case, I had 1200 ferritin levels, so 500 does not seem so high. But that would be if you had that level for a short period of time, having 500 ferritin for a long period of time is not usual and should be taken into consideration. Also tell you that inflammatory processes in the liver raise ferritin as well as the presence of cirrhosis, so it must be studied and rule out that iron deposits are being generated in the liver.Above all ask your doctor.

[Roxanne9]

Thank you.

[nash2 Partner]

Before I had gall bladder surgery and before I ever heard of NASH, my ferritin was over 1400. It was a symptom of my condition rather than a cause. Some have a genetic disposition to depositing iron in the liver which is a problem but they have genetic test for that, hemachromatosis, I don't have that but we do schedule a phlebotomy if my iron levels get high as a precaution.

[Realy in reply to nash2]

I saw a video of a Dr in the UK said that if someone had elevated ferratin at time of fibroscan it should be repeated after levels normalize, i guess if you have elevated ferattin that would be ongoing inflammation that would affect liver stifness. 🤷‍♂️

[nash2 Partner in reply to Realy]

It is a sign that something is annoying the liver. If it goes down in a couple of months, probably viral, if not it suggests more analysis.

[Realy in reply to nash2]

But I’m assuming it could falsely elevate a fibroscan reading and I guess that’s why they would want a repeat to see if change?

[nash2 Partner in reply to Realy]

yes

[isi123 in reply to nash2]

Nash2, did they rule out hemochromatosis because you are not homozygous? There is a great discussion about heterozygous carriers and the phenotypic expression of the disease, when it is associated with other metabolic problems. Many times you are excluded from the diagnosis because you are not homozygous, a point I have discussed with several doctors. Did they quantify the LIC (liver iron content)? I think the clearest indicator of excessive absorption by the body is transferrin saturation.

[wifeofnafld]

My husband had a high ferritin level also, in the 700s I believe. His liver specialist said it means there is inflammation present, and she wasn't too concerned. Said we should retest in 3 months and if it is still high we will do some additional testing.

[Realy in reply to wifeofnafld]

I would think that could increase liver stifness