Granulomatous Hepatitis

[Samson4]

My biopsy showed I have have granulomatous hepatitis with stage 3-4 fibrosis and moderate fatty liver. They don't know what the granulomas are from. Trying to figure out if losing weight will even help me as I don't know if the granulomas are causing the fibrosis. I know losing weight is good either way, but would Luke to know the chances that the granulomas is the problem. Thanks

[nash2 Partner]

The causes of liver granulomas are legion. Infectious disorders are the most important: bacterial (eg, TB and other mycobacterial infections, brucellosis, tularemia, actinomycosis); fungal (eg, histoplasmosis, cryptococcosis, blastomycosis); parasitic (eg, schistosomiasis –the most important worldwide, toxoplasmosis, visceral larva migrans); viral infections, which are less common so without further testing there is no telling but if related to NAFLD often disappear with weight loss.

[Samson4 in reply to nash2]

I had some tests done. I know I had tb test, and some others, but not sure about these others. None sound familiar. I am wondering if there is treatment for any of these. I see a doc at John's Hopkins and I hope he did all the tests I needed. They pretty much said it could be from crohns or liver injury from meds, but have no idea really. Therefore no treatment. I just hope they did all the tests that were needed.

[nash2 Partner in reply to Samson4]

Hopkins is well respected so you are probably in good hands there.