Has anyone here ever tried LDD (low dose dipyridamole) for their ED? There is not so much information about it on the internet as it is a very new medicine. There was an article was published about it on Medium.com
Waiting to hear from you all
The information below is excerpted from the patent filed for Low Dose Dipyridamole:
Erectile dysfunction treatment
In order to determine the effect of low dose oral dipyridamole for treating erectile dysfunction, 5 subjects with erectile dysfunction were treated with low dose oral dipyridamole prepared as in Example 1 as the sole treatment. Some subjects had either failed or could not tolerate conventional treatments.
Subject 1 (41 y/o male), Subject 2 (27 y/o male), Subject 3 (67 y/o male), Subject 4 (70 y/o male) and subject 5 (48 y/or male) were treated with varying doses (2, 3, 5 and 10 mg) taken in the evening or before sleep, for periods 2 weeks or more for each dose and followed for up to 15 months of use in total.
Subject 1: 2 mg was found to be the optimal dose for complete restoration of erectile function that had not been present for 6 years including absence of nocturnal penile tumescence for 12 years. The subject could not take sildenafil or similar agents due to adverse side effects. A consistent daily dose of dipyridamole was taken at night on a continuous basis. Nocturnal penile tumescence effect was experienced sooner (noticed if waking up in middle of the night) if taken on empty stomach, but always upon awakening in the morning. Additional effects included excellent dream recall, vivid dreams and improved sleep.
Subject 2: 3 mg was found to be the optimal dose for obtaining satisfactory erectile function. Subject 2 had not been able to achieve an erection for 3 years without the use of sildenafil, tadalafil or vardenafil. An additional effect included improved sleep.
Subject 3: Erectile function was restored to user's satisfaction within 10 days of starting dipyridamole at 2mg. For a period of time, the subject increased dose to twice daily, still with satisfactory outcome. When the subject increased dose to lOmg daily, the beneficial effect was lost.
Subject 4: Resolution of erectile dysfunction was achieved within 5 days of starting low dose oral dipyridamole at 2mg. As the subject was satisfied with the result, no dose adjustment was attempted. The subject noticed increased resistance to upper respiratory viral infections (or colds) which now rarely occurred, as opposed to previous incidence of every 2 - 3 months.
Subject 5: Erectile dysfunction resolved within 2 weeks of starting low dose oral dipyridamole at 2 mg. The subject found that when taken with food, 2 mg was not that effective but 5 mg was. However 10 mg did not produce the same benefit as 5 mg. The subject also found that use of low dose oral dipyridamole alleviated his long-standing depression. The subject was no longer using SSRI's due to their risk of causing erectile dysfunction.
This example illustrates that low dose oral dipyridamole is effective for the treatment of erectile dysfunction and suggests that it is a viable substitute for drugs currently approved for erectile dysfunction.
