Endometriosis UK

Decapeptyl Injection

After worrying about having a decapeptyl injection and reading many horror stories, I can say I was worrying unnecessarily. It has been a week since the injection and so far so good. The first 2 days I had a bit of dizziness and a bit of a headache, but since then nothing. I think sometimes, people only post the bad things and you tend not to hear about anything good xx

9 Replies

Could you tell me more about this injection please Miranda? Is this for lower back and abdomen pain? Fantastic news that it has helped you! I hope that continues to be the case :) xx


Its true! We focus on the side effects and not the positive effects hormone treatment can have on our endo symptoms! Long may it continue to work for you.


I have only had the injection for pre op purposes. Apparently it helps to shrink the endo before surgery. I am having a total hysterectomy and excision of the endo. I am keeping my ovaries, the gynae said it will help to keep me young!!! Don't really care about that just want to be pain free, but we will see. Only 3 weeks tomorrow before op :-( Stating to get a little apprehensive now., I have made a list of things to sort before I go in, even down to remember fathers day cards, go shopping for my daughters prom shoes!! (how sad am I).

I am very fortunate that I do have 2 children (16 & 12) I did loose 3 in between and I can't imagine how awful it must be for many out there who are unable to have children because of this wretched disease xx


Hi Miranda

Glad you put some positive comments on here it is nice to hear for a change. Also glad your not suffering with any side effects.

Do you mind me asking are was your loosing 3 in between linked to your endometriosis? I have recently found out I have endo and my aunty also has it. She has had about 7 miscarriges so I'm just wondering if this may be a common thing. I am concerned about this as I haven't had any children yet and have been concerned about my future fertility although I have never tried to get pregnant before. xxx



To be honest no one has ever linked the two. When I did eventually manage to get pregnant again, I had a scan every week to make sure he was still there. I recently found out that I also have Strep B, but again nothing has ever been said.

I feel very lucky that I did manage to have 2 children as I know there are many women that are unable. I did have my children young, my first was at 22 and i'm now 38!! I don't think I would have considered a hysterectomy before now.

Hope this helps xx


Yes it does thankyou xxx


hi there

i have been on decapeptyl injection for a year now. I was put on it after having my endo lasered through laproscopy . the first 6 months were amazing i was pain free pretty much for all that time and my quality of life certainly improved. the last 6 months my side effect symptoms have been not great mainly the joint pain the hrt does help but not pain free anymore - however i would like to point out that its unusual to be on this injection unlicensed as i am as usually maximum length of use is 6 months. I would defiantly use this form of pain relief and endo control short term again :)


Hi Jemmadavies88,

could you tell me pls what happened after the injections were stoped? Did endo recurred?

Hope you are pain free! x



Hi, how long did it take b4 you noticed a difference from the injection please?

I’ve had 2 so far and not had much improvement. My sleeping has gotten worse though. I’m back at the hospital next wk for my third injection x


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