Prostap injections side effects - Endometriosis UK

Endometriosis UK

70,734 members52,159 posts

Prostap injections side effects

thearoma4 profile image
5 Replies

hi. I had my first prostap injection 10 days ago. I’ve been in agony. Even worse than my normal endo pain and now severely heavy bleeding. Is this normal?? Feel so unwell

Written by
thearoma4 profile image
thearoma4
To view profiles and participate in discussions please or .
Read more about...
5 Replies
Sabrinacolada profile image
Sabrinacolada

Hi,

Sorry you are in so much pain. I have also quite recently started gnrh agonist injections, it's zoladex but is comparable to prostap.

I was told that for the first 2-4 weeks after injection there will be an oestrogen surge and this will make endometresiosis/ pain much worse. Thus I had expected the worst endo flare up. I was personally OK until about 14 days in then had stabbing pelvic pain, some bleeding and cramps ( for about a week on and off). It settled with naproxen combined with Solpadol (only needed a few odd days). Thankfully they were fleeting and I was still able to have a relatively normal Xmas.

I am about a month in now, I've had quite bad joint pain intermittently ( some days last week I felt like an 80 year old stiff and stabbing joint pain) and the odd few headaches. I saw the specialist last Thursday he said all likely side effects of induced menopause but says to wait until about 2 months which is when I can see if the injections have worked ( he says 9 out of 10 women find it sucessful so worth sticking it out for now).

I've not had any hot flushes, no bouts of severe endometresiosis pain ( that I had prior to starting which ended up in hospitalisation on occasion). But I am also on add back hrt - tibilone since day 1.

I found when pain flared up in my case very intense pelvic stabbing pain it was better to take an nsaid at the first onset and for a few days after ongoing then to wait. The solpadol ( codeine and paracetemol) I used sparingly as I suffer badly with constipation due to rectovaginal endo. Hot water bottles at night.

Hopefully you get some releif hun. I told myself it's like riding out a storm. Thunderstorms won't last forever and hopefully in a couple of months we will both be much better off for it. If it gets really bad or pain releif isn't working maybe try and speak to a doctor.

❤ Sabrina x

thearoma4 profile image
thearoma4 in reply to Sabrinacolada

thank you. My pain has eased off slightly but now I’ve got severe migraines. Almost unbearable. Like you said, just need too ride it out. Hopefully will all be ok soon. X

Sabrinacolada profile image
Sabrinacolada in reply to thearoma4

Sorry to hear that. Hopefully you get some relief soon. I had very severe headaches and a weird head cold feeling for about 4 days ( woke up fine but by afternoon started to kick in). Thankfully all seems normal now. Hopefully for you too x

Prettythings1 profile image
Prettythings1

i have been having prostap i injections for over six months

when I first started them the pain was horrendous, then it got much better it eases off just persevere. I think it is meant to get worse before it gets better.

CryBaby91 profile image
CryBaby91

I was on Gonapeptyl, which is basically the same lol. I had 5 injections, pain was CRAZY that first 2 months. I vomitted like mad too! But after that it massively calmed down. My issue was the impact on my mental health, and concentration issues/dizzy spells. It was limiting my ability to study at university, which was the last straw. I've been off them since November and I'm still waiting for my cycle to return to normal, pain is increasing. It's been hard I won't lie! But the risks long term worried me, and for me personally it was just too many negatives for the small positive of REDUCED pain (it wasn't a 100% cure).

You may also like...

Side effects after second prostap injection

this morning feeling worse than ever. Pain is horrendous but also full of cold and feel extremely...

First monthly Prostap injection - side effects two weeks in…

similar to mine… Had my first monthly Prostap injection at my GP surgery two weeks ago. Got told I...

Prostap side effects.

Morning ladies, I need your help. I had my first prostap injection on Thursday, 1 of 6, 1 a...

Prostap and side effects

my endo pains are coming back. What are your experiences for those who have prostap injections? And

Prostap side effects

doing well!I started prostap on the 18th of September and today had my third injection. It's only...