Can Zoladex cause anger/rage? I feel like I'm going mad...

[kelbel]

Please help,

I have been on the Zoladex injection for 3 months now and have noticed this last month I have been experiencing extreme

anger.

The smallest of things seem to set me off, I have never experienced anger like it, I change completely, I literally feel so angry I want to "hurt" myself, there is no in between mood, I just go from calm to kill in the click of a finger... Is this normal or am I going mad??

I have 3 more injections to have, but am scared to feel like this for a further 3 months.

Has anyone else experienced anything similar whilst being on Zoladex please?

Any advice welcome.

Kelly

[Hidden]

I feel the same. Ive recently had zoladex and my mood splits instantly. One min im crying then im shouting and anything will set me off. I spoke to the nurse about it and its the injection and menopausal state which sends you this way and will hopefully wear off. I understand exactly what you mean about the hurting yourself or hoe you react. My poor bf is lucky ive not hit him the way he snores. Hope this helps hun. Here if you need xx

[kelbel in reply to Hidden]

Thank you Septimus00

It's good to know I'm not alone, however I wish none of us were going through these symptoms! I'm so glad you understand what I mean about wanting to hurt myself, as these symptoms are what scares me the most!.. It's stupid as I am the most passive person you could meet, but when I go into one of my rages It's not me at all!!... I have long black hair and the amount of times I have gone to cut it off is ridiculous! ...I just go into "The Red Zone"!!

By the time these injections are over, I will have either gone mad or be bald!! Lol

Thank you for replying, it helped a lot.

Kelly xx

[NB1234]

Hi, Yes I am the same. I was on zoladex for 12 months, I actually felt ok then, the mood swings were occasional. But now that im back on it or another version of it called prostrap i feel all over the place. I find myself crying over anything, and wanting to throw things at anyone who annoys me. Its usually my poor husband who gets to be in the middle of these mood swings. I spoke to the doctors who said this can be normal. Are you on HRT at the same time, as this is suppose to help.

Your not alone, I hope you start to feel better soon.

Here if you need to chat

Nicki

[kelbel in reply to NB1234]

Hi Nicki,

Yes I am on HRT gel also, but only started this 2 days ago, as when I was 18 I had a DVT following an accident, so my consultant has been wary to use it as if you have ever had a thrombosis you should avoid HRT like the plague!!

I'm not sure how long it takes to kick in though! Any ideas??

Thank you for responding, it's so comforting to know I'm not alone!

Kelly xx

[superstorm82]

Yes me too. I have always been a passive person but not at the moment. I feel stressed and anxious for no reason. Then I go horrid and spiteful followed by as you call it 'kill'. That then makes me more upset because I know its not me. Its a vicious circle. I am at the same point as you my love, month 3 and it has only been over the last 3weeks or so I have noticed it. Also have you lost your motivation? I had a day off yesterday and liturally sat in my underwear watching come dine with me...all day! Then my fiance got home from work and I got angry that he didnt read my mind and start dinner. (Which meant i hadoto get off the couch) I know this is absurd but at the time made me hate him. I feel like im going crazy.

[kelbel in reply to superstorm82]

Morning Superstorm82

I couldn't help but smile when reading your reply as we sound so similar! I too am a very passive person, so these anger stages like you say are even more upsetting. My husband said yesterday that he has stopped making jokes or saying anything that I could possibly take the wrong way, as he's scared to upset me as he knows that I can just "flip" over the slightest things.

He's actually very good and keeps telling me it's the injections and not me, but when your the one going through this sudden change its scary.

As for motivation I have none, I am currently signed off of work with Endometriosis and depression. The last 2 months have been the hardest of my life... Not only are my hormones all over the place with this injection, but Iv'e been put on antidepressants, so I have a multitude of side effects going on.

Please don't think you are going crazy, what you said rings so many bells for me, you're not alone!

Please feel free to message me is you ever need a chat, I can't promise to help but at least you will know I understand!

Kelly xx

[superstorm82 in reply to kelbel]

Thank. Actually having a better day today and my other half is just being amazing. Aren't we lucky to have such great men to help us through this horrid spell. I am really putting him through it and being more trouble than i am sure i am worth. Dont know about you but I couldn't handle any of this without him. x

[CharlieSays]

I had mood swings and depression on my first course of Prostap last year, but this time around have taken HRT and been nowhere near as bad (I always got the 'wanting to kill someone' thing just before my periods anyway and my husband is very good at lighting the fuse - you think he'd have learnt by now, LOL!). The HRt took a week or so to kick in, I think.

[Impatient]

me too- luckily mum knew me well enough to know that my rages were so completely out of character that it must be the zoladex and she was fantastic about it and bore the brunt of my shouting swearing, slamming doors, and everything else i have forgotten but must have put her through. I got her a big bunch of flowers after stopping treatment to say sorry and thank you for taking care of me.

The worst aspect is I had no control over it, other than to shut myself away in the bedroom away from everyone else for their own safety. I would get angry as the most ridiculously silly things: lights too bright, tv too loud( it wasn't), kids playing, lorries driving up the road, didn't matter the cause, the frustrations and exhaustion from months of no more sleep than 20 minutes as a time between hot flushes and all the other incessant side effects just wore me to a frazzle. Aside from that was the lack of hormones to calm me down. I wasn't on HRT, it wasn't offered and I didn't know it was an option.

Mercifully that all stopped pretty quickly when I stopped the zoladex. I was the evil witch from hell at home - teenage temper tantrums way above and beyond anything I actually experienced as a teen.

So in answer to your question - most definitely this is the zoladex and much like you, had I been driving a car and someone cut me up - I would have killed, I was that angry at everything. Normally I don't swear and wouldn't say boo to a goose. A really chilled out character, so the moods and anger were something that terrified me as well as everyone else too.

My advice is stop the zoladex.

It doesn't cure or kill endo, it is ONLY prescribed to try an improve your quality of life for a short time, and when it hasn't done that there is no point at all putting yourself through another month of this..and no point putting your nearest and dearest through it either, because they too suffer when you do switch to psycho mode.

I stopped at 4 months but should have stopped sooner. Id much rather have just two extra periods in my life that put myself and everyone else through the hell of remaining on zoladex. It simply isn't worth it.