I didn't inherit the MODY gene but it runs in my mothers side of the family - my brother drew the short straw and does have the MODY gene. They started off by assuming he was type 2 and put him on metformin to which he didn't respond - but did respond when switched to drugs the right drugs.
I was rather shocked last week when I looked through my mothers medication and found out that she was on metformin as she has MODY, but may be it is possible to have MODY and be type 2 and that is why she is on metformin.
I suffer from an inability to absorb B12. There is an awful lot of overlap between the symptoms of B12D and diabetes when it comes to cellular damage and neuropathy and I'm a bit concerned that my mother may have undiagnosed problems with B12D going on - her memory is bad (yes, no that could be age and diabetes), she gets confused, has been suffering from endless infections (currently left with no hearing as she battles with a series of ear infections) and she recently developed a bleed that sounds like it could be endometriosis (has thickening of the womb), her gait reminds me of mine before I got my B12 treatment sorted out ... When I went through her meds she was on 4 drugs which are known to potential suppress absorption of B12 - my grandmother - mother's mother - had a lot of symptoms in her last few years that now make me wonder about B12D - including depression, a stroke, and muscle spasms - admittedly she was 94 and B12D gets more likely with age ... but my grandfather - from whom my mother inherited the MODY gene had problems with dementia that may me wonder if B12 was implicated, particularly as there is a strong correlation between diabetes and B12.
Anyway, in the process of writing to my mothers GP but just wondering if anyone knows if it is possible to have MODY and type 2 ... or has some practical experience of overlap of MODY and B12, or even type1 and B12