Side effects of metformin 1000g per day

[jkbassin]

[Hidden]

You are likely to get metallic taste in your mouth.

[kvn2013]

As per my Doctor an Endocrinilogist (Diabetic Metabolism) metroformin is linked with damage of kidneys( known by Creatinine, pottassium and sodium, protein values in your blood test

[managediab]

Metformin 1000g means a Kg per day. Think it is 1000mg per day. Lactic acidosis, flatulence re general side effects.

[jkbassin]

I am sorry. Its 1000mg or 1g SR slow release taken at night time alo0ng with Zoryl 1mg in the morning.

[jkbassin]

can Lactic acidodsis lead to iron deficiency in body and low Hb levels?

[sarojini]

presence of microalbumin &pritien in uriene of duabeticpatients should stop metformin it will damage your kidney sarojini

[sarojini]

metformin is not at all recommended to diabetic patient who possess protin & albumin ie alb uminaria , protineria generally diabetoligists not recommending metformin since metformin damage kidney sarojini

[Hidden]

From NET:

Metformin Side Effects:

Lactic Acidosis:This is potentially the most serious of the metformin side effects. The uptake of lactate by the liver is effected by metformin in a negative way. If the kidneys do not process the excess lactate the blood of the patient will acidify which can lead to a whole slew of problems. For example: anxiety, hyperventilation, irregular heart rate nausea and in some cases vomiting. This is the reason that metformin is generally only prescribed to people with a healthy kidney function..

Gastrointestinal problems:The most common of metformin side effects. Clinical trials show that as much as 50% of the patients prescribed metformin are affected by this type of problems. While this is not the most serious of side effects of metformin it can still cause extreme discomfort. These are some of the symptoms of gastrointestinal discomfort: nausea, cramps, vomiting, diarrhea and it is often accompanied by flatulence. Fortunately these side effects are most common when the drug is first prescribed or when the dosage is changed. For this reason the starting dose is often fairly low and will slowly be increased to the required levels. This way the body of the patient has the time to react to the changing circumstances. Once the patient is used to the required dose they are unlikely to keep experiencing these adverse effects. However, one problem that can manifest itself after prolonged usage of metformin is that B12 can no longer be properly absorbed. This will lead to a B12 deficiency and a close eye needs to be kept on long term patients for this reason. A prolonged B12 deficiency can cause damage to the nerve system. The symptoms will usually only manifest themselves after a decade and in some cases even longer. By that time the damage can already be irreversible. As a B12 deficiency is often hard to detect, usually preventative measures are taken to avoid this fairly serious side effect.

General Advice When Dealing With the Side Effects of Metformin

As you can see there are still quite a few serious metformin side effects that can have an effect on the lives of its users. However, almost all of these are not life threatening, with the exception of lactic acidosis. When proper care is taken to slowly build up the dose of the drug one should only experience mild discomfort, unless there are underlying health issues, such as a reduced kidney function. For this reason, among others, you should never increase the dose by yourself, but always contact the health professional that prescribed you the medication.