Statins may speed up Parkinson's onset

[rksharmakumar]

A study has found that fat soluble statins, medications used to reduce levels of cholesterol in the blood may speed up the onset of symptoms of Parkinson's in people, susceptible to the disease. Parkinson's disease is a disorder of central nervous system that affect movement. Previous research has suggested that statins may protect against Parkinson's. Research has been inconsistent, however, with various study showing a lower risk, or no difference or higher risk of Parkinson's in statins users. The new study says statins use were associated with higher, not lowe, Parkinson's risk, and the association was more noticeable for lipophilic statins, an observation inconsistent with the current hypothesis that these statins protect nerve cells.There are two types of stains. Water soluble statins can not get in to the brain, while fat soluble stains called lipophilic can. The team analysed data for more than 50 million people under 65. They found that prior stain use was associated with higher risk of Parkinson's and was more noticeable during the start of the medication use. The research is published in the Journal of Movement disorder.

[ramana42 Volunteer]

Just for information,can you please name the fat soluble and water soluble statins?

[gangadharan_nair in reply to ramana42]

Statins can be classified into water soluble and lipid soluble (lipophilic) statins

.

* Water soluble statins -- pravastatin and rosuvastatin

* Lipid soluble statins -- atorvastatin, cerivastatin, fluvastatin, lovastatin and simvastatin

Source:--

gpnotebook.co.uk/simplepage...

[ramana42 Volunteer in reply to gangadharan_nair]

Spot on,as usual.

[Tibblington]

I very much like your line of argument which is totally logical. The brain comprises a fatty substance to maintain separation between the cells so what you are saying supports the hypothesis.

When you interfer with one mechanism in the body all too often you have to interfer with another to counter the side effects of the first. Big Phama has a lot to answer for and so do some of the medical profession who blindly follow what the pharmaceutical industry tells them.

One has to ask why we have an increase in mental disorders like Parkinsons and Alzheimers? I would suggest another cause and that was the rush to convert to the polyunsaturated fats and seed oils which are not natural food for man; to quote T.L. Cleave FRCP "we are not finches". We have always eaten the saturated fats why on earth should they start being bad for us?

You are obviously someone who thinks things through, don't stop.