The artificial sweetener sucralose, better known by its brand name Splenda, has been on the US market for fifteen years.
US –FDA had approved Splenda in 1998 based on more than 110 safety studies , only two of which were actually conducted on humans, a total of 23 people..
The Center for Science in the Public Interest (CSPI) has now finally downgraded Splenda from its former “safe” category to one of “caution” following an unpublished study ( in Italy) that found Splenda may cause leukemia in mice…at last an ALARM.
The track record of CSPI is not great:
It spearheaded a campaign against the use of healthful saturated fats during the 1980s, touting trans fats as a healthier alternative to palm oil and coconut oil..
CSPI reversed their position on synthetic trans fats in1990s citing it as the greater public health danger, but the damage had already been done.
Is "Caution" the right word?...
Splenda is a synthetic chemical created in a laboratory. In the five-step patented process of making it, three chlorine molecules are added to one sucrose (sugar) molecule. Some will argue that natural foods also contain chloride, which is true.
•However, in natural foods, the chloride is connected with ionic bonds that easily dissociate. In Splenda, they're in a covalent bond that does not dissociate. In fact, there are NO covalent chloride bonds to organic compounds in nature, only ionic. Covalent chloride bonds only exist in synthetic, man-made molecules such as DDT, PCBs.
Your body has no enzymes to break down this covalently bound chloride. Why would it? It never existed in nature, so the human body never had a reason to address it. And since it's not broken down and metabolized by your body, they can claim it to be non-caloric—essentially, it's supposed to pass right through you. However, the research (which is primarily extrapolated from animal studies) indicates that about 15 percent of sucralose IS in fact absorbed into your digestive system, and ultimately stored in your body.
Splenda May Wreak Havoc Within Your Digestive Tract
Splenda has been found to be particularly damaging to your intestines. A study published in 2008 found that Splenda:4
•Reduces the amount of beneficial bacteria in your intestines by 50 percent
•Increases the pH level in your intestines
Further, some of the initial studies done on Splenda revealed:
•Decreased red blood cells -- sign of anemia -- at levels above 1,500 mg/kg/day
•Increased male infertility by interfering with sperm production and vitality, as well as brain lesions at higher doses
•Enlarged and calcified kidneys
•Spontaneous abortions in nearly half the rabbit population given sucralose, compared to zero aborted pregnancies in the control group
•A 23 percent death rate in rabbits, compared to a 6 percent death rate in the control group
Worse still, the longest of the two human trials conducted on Splenda lasted only four days and looked at sucralose in relation to tooth decay, not human tolerance! So if you’ve been ingesting Splenda for years, you’re actually acting as a human guinea pig, as no one knows what happens when humans consume this substance for long periods.
Aspartame Also Linked to Leukemia
Splenda is not the only artificial sweetener that has been linked to leukemia. The longest-ever human aspartame study, spanning 22 years, found a clear association between aspartame consumption and non-Hodgkin’s Lymphoma and leukemia in men.
The long-term nature of this study is really crucial because one of the primary tricks manufacturers use to hide the toxicity of their products are short-term trials. The longest study prior to this one was only 4.5 months, far too short to reveal any toxicity from chronic exposure. Unfortunately, because there are so many of these short-term trials, manufacturers get away with saying that aspartame is one of the most studied food additives ever made and no health concerns have ever been discovered. Splenda’s maker has used similar tricks as well.
Aspartame is primarily made up of aspartic acid and phenylalanine. The phenylalanine has been synthetically modified to carry a methyl group, which provides the majority of the sweetness. That phenylalanine methyl bond, called a methyl ester, is very weak, which allows the methyl group on the phenylalanine to easily break off and form methanol. This is in sharp contrast to naturally-occurring methanol found in certain fruits and vegetables, where it is firmly bonded to pectin, allowing the methanol to be safely passed through your digestive tract.
Methanol acts as a metabolic Trojan horse; it's carried into susceptible tissues in your body, like your brain and bone marrow, where the ADH enzyme converts it into formaldehyde, which wreaks havoc with sensitive proteins and DNA. All other animals, on the other hand, have a protective mechanism that allows methanol to be broken down into harmless formic acid… but, according to aspartame expert Dr. Woodrow Monte, there's a major biochemical problem with methanol in humans, because of the difference in how it's metabolized, compared to all other animals. This is why toxicology testing on animals is a flawed model. It doesn't fully apply to humans who are unable to convert the toxic formaldehyde into harmless formic acid.
Dr. Mercola recommends stevia,(NOT POWDERS (PROCESSING INVOLVED) in liquid form, a natural plant that has been around for over 1,500 years, He says ”it is required only as few drops to sweeten a drink).; Cautions and says” That said, like most choices, especially sweeteners, I recommend using it in moderation, just like sugar.”
IT IS YOUR HEALTH....YOUR CHOICE .. MAKE INFORMED CHOICES